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Mouse Anti-TES Recombinant Antibody (CBYJT-2555) (CBMAB-T1713-YJ)

Provided herein is a Mouse monoclonal antibody, which binds to TES (Testin LIM Domain Protein). The antibody can be used for immunoassay techniques, such as ELISA, IF, IHC, WB.
See all TES antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBYJT-2555
Antibody Isotype
IgG1, κ
Application
ELISA, IF, IHC, WB

Basic Information

Immunogen
Human Testin (aa1-422) with GST Tag
Specificity
Human
Antibody Isotype
IgG1, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Buffer
PBS, pH 7.2, 40% Glycerol
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Epitope
aa 1-422

Target

Full Name
testis derived transcript (3 LIM domains)
Introduction
Cancer-associated chromosomal changes often involve regions containing fragile sites. TES maps to a commom fragile site on chromosome 7q31.2 designated FRA7G. TES is similar to mouse Testin, a testosterone-responsive gene encoding a Sertoli cell secretory protein containing three LIM domains. LIM domains are double zinc-finger motifs that mediate protein-protein interactions between transcription factors, cytoskeletal proteins and signaling proteins. TES is a negative regulator of cell growth and may act as a tumor suppressor. This scaffold protein may also function in cell adhesion, cell spreading and in the reorganization of the actin cytoskeleton.
Entrez Gene ID
26136
UniProt ID
Q9UGI8
Alternative Names
Testin LIM Domain Protein; Testis Derived Transcript (3 LIM Domains); TESS; TESS-2; Testin
Function
Scaffold protein that may play a role in cell adhesion, cell spreading and in the reorganization of the actin cytoskeleton. Plays a role in the regulation of cell proliferation. May act as a tumor suppressor. Inhibits tumor cell growth.
Biological Process
Negative regulation of cell population proliferation
Cellular Location
Cytoplasm
Cell junction, focal adhesion
Detected along actin stress fibers.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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