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TNFRSF10C

The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contains an extracellular TRAIL-binding domain and a transmembrane domain, but no cytoplasmic death domain. This receptor is not capable of inducing apoptosis, and is thought to function as an antagonistic receptor that protects cells from TRAIL-induced apoptosis. This gene was found to be a p53-regulated DNA damage-inducible gene. The expression of this gene was detected in many normal tissues but not in most cancer cell lines, which may explain the specific sensitivity of cancer cells to the apoptosis-inducing activity of TRAIL. [provided by RefSeq]

Full Name

tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain

Function

Receptor for the cytotoxic ligand TRAIL. Lacks a cytoplasmic death domain and hence is not capable of inducing apoptosis. May protect cells against TRAIL mediated apoptosis by competing with TRAIL-R1 and R2 for binding to the ligand.

Biological Process

Biological Process positive regulation of apoptotic process Source:GO_Central1 Publication
Biological Process TRAIL-activated apoptotic signaling pathway Source:GO_Central1 Publication

Cellular Location

Cell membrane

PTM

N-glycosylated and O-glycosylated.

Anti-TNFRSF10C antibodies

Mouse Anti-TNFRSF10C Recombinant Antibody (CBYJT-3664) (CBMAB-T3033-YJ)

SDS

Target: TNFRSF10C

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: CBYJT-3664

Application*: F, IP

Mouse Anti-TNFRSF10C Recombinant Antibody (CBYJT-3666) (CBMAB-T3035-YJ)

SDS

Target: TNFRSF10C

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: CBYJT-3666

Application*: F, MC

Mouse Anti-TNFRSF10C Recombinant Antibody (CBYJT-3669) (CBMAB-T3041-YJ)

SDS

Target: TNFRSF10C

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: CBYJT-3669

Application*: WB, IH, P

Mouse Anti-TNFRSF10C Recombinant Antibody (10B1169) (CBMAB-D2306-YC)

SDS

Target: TNFRSF10C

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: 10B1169

Application*: F, IP

Mouse Anti-TNFRSF10C Recombinant Antibody (CBYJT-3663) (CBMAB-T3032-YJ)

SDS

Target: TNFRSF10C

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: CBYJT-3663

Application*: IH, WB

Mouse Anti-TNFRSF10C Recombinant Antibody (CBYJT-3665) (CBMAB-T3034-YJ)

SDS

Target: TNFRSF10C

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: CBYJT-3665

Application*: WB, P

Mouse Anti-TNFRSF10C Recombinant Antibody (CBYJT-3667) (CBMAB-T3038-YJ)

SDS

Target: TNFRSF10C

Host: Mouse

Antibody Isotype: IgG1, κ

Specificity: Human

Clone: CBYJT-3667

Application*: E

Mouse Anti-TNFRSF10C Recombinant Antibody (HS301) (CBMAB-T3039-YJ)

SDS

Target: TNFRSF10C

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: HS301

Application*: F, IC

Rat Anti-TNFRSF10C Recombinant Antibody (CBYJT-3668) (CBMAB-T3040-YJ)

SDS

Target: TNFRSF10C

Host: Rat

Antibody Isotype: IgG2a

Specificity: Human

Clone: CBYJT-3668

Application*: F, WB

Mouse Anti-TNFRSF10C Recombinant Antibody (TR3.06) (CBMAB-T3042-YJ)

SDS

Target: TNFRSF10C

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: TR3.06

Application*: F, IH, WB

Mouse Anti-TNFRSF10C Recombinant Antibody (CBYJT-3670) (CBMAB-T3043-YJ)

SDS

Target: TNFRSF10C

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: CBYJT-3670

Application*: F, MC

Mouse Anti-TNFRSF10C Recombinant Antibody (6D346) (CBMAB-D2307-YC)

SDS

Target: TNFRSF10C

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: 6D346

Application*: F, IC

Mouse Anti-TNFRSF10C Recombinant Antibody (B-D44) (CBMAB-D2308-YC)

SDS

Target: TNFRSF10C

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: B-D44

Application*: F, I

Mouse Anti-TNFRSF10C Recombinant Antibody (B-H47) (CBMAB-D2309-YC)

SDS

Target: TNFRSF10C

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: B-H47

Application*: WB

Mouse Anti-TNFRSF10C Recombinant Antibody (TRAIL-R3-02) (CBMAB-D2310-YC)

SDS

Target: TNFRSF10C

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: TRAIL-R3-02

Application*: F

Rat Anti-TNFRSF10C Recombinant Antibody (6D347) (CBMAB-D2312-YC)

SDS

Target: TNFRSF10C

Host: Rat

Antibody Isotype: IgG2a

Specificity: Human

Clone: 6D347

Application*: F, WB

Mouse Anti-TNFRSF10C Recombinant Antibody (2B8) (CBMAB-C0842-LY)

SDS

Target: TNFRSF10C

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: 2B8

Application*: P, F

Mouse Anti-TNFRSF10C Recombinant Antibody (3A1) (CBMAB-A9259-LY)

SDS

Target: TNFRSF10C

Host: Mouse

Antibody Isotype: IgG1, κ

Specificity: Human

Clone: 3A1

Application*: WB, E

Mouse Anti-TNFRSF10C Recombinant Antibody (4D12) (CBMAB-A9260-LY)

SDS

Target: TNFRSF10C

Host: Mouse

Antibody Isotype: IgG1, κ

Specificity: Human

Clone: 4D12

Application*: WB, E

Mouse Anti-TNFRSF10C Recombinant Antibody (4G7) (CBMAB-A9261-LY)

SDS

Target: TNFRSF10C

Host: Mouse

Antibody Isotype: IgG1, κ

Specificity: Human

Clone: 4G7

Application*: WB, E

Mouse Anti-TNFRSF10C Recombinant Antibody (8B8) (CBMAB-A9262-LY)

SDS

Target: TNFRSF10C

Host: Mouse

Antibody Isotype: IgG1, κ

Specificity: Human

Clone: 8B8

Application*: E, E

Mouse Anti-TNFRSF10C Recombinant Antibody (CBWJC-4517) (CBMAB-C5910WJ)

SDS

Target: TNFRSF10C

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: CBWJC-4517

Application*: WB

Mouse Anti-TNFRSF10C Recombinant Antibody (DJR3) (CBMAB-C1743-CQ)

SDS

Target: TNFRSF10C

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: DJR3

Application*: F

For Research Use Only. Not For Clinical Use.

(P): Predicted

* Abbreviations

IFImmunofluorescence

IHImmunohistochemistry

IPImmunoprecipitation

WBWestern Blot

EELISA

MMicroarray

CIChromatin Immunoprecipitation

FFlow Cytometry

FNFunction Assay

IDImmunodiffusion

RRadioimmunoassay

TCTissue Culture

GSGel Supershift

NNeutralization

BBlocking

AActivation

IInhibition

DDepletion

ESELISpot

DBDot Blot

MCMass Cytometry/CyTOF

CTCytotoxicity

SStimulation

AGAgonist

APApoptosis

IMImmunomicroscopy

BABioassay

CSCostimulation

EMElectron Microscopy

IEImmunoelectrophoresis

PAPeptide Array

ICImmunocytochemistry

PEPeptide ELISA

MDMeDIP

SHIn situ hybridization

IAEnzyme Immunoassay

SEsandwich ELISA

PLProximity Ligation Assay

ECELISA(Cap)

EDELISA(Det)

BIBioimaging

IOImmunoassay

LFLateral Flow Immunoassay

LALuminex Assay

CImmunohistochemistry-Frozen Sections

PImmunohistologyp-Paraffin Sections

ISIntracellular Staining for Flow Cytometry

MSElectrophoretic Mobility Shift Assay

RIRNA Binding Protein Immunoprecipitation (RIP)

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