TPSG1

Tryptases comprise a family of trypsin-like serine proteases, the peptidase family S1. Tryptases are enzymatically active only as heparin-stabilized tetramers, and they are resistant to all known endogenous proteinase inhibitors. Several tryptase genes are clustered on chromosome 16p13.3. Currently four functional genes - alpha I, beta I, beta II and gamma I - have been identified. And beta I has an allelic variant named alpha II, beta II has an allelic variant beta III, also gamma I has an allelic variant gamma II. Beta tryptases appear to be the main isoenzymes expressed in mast cells; whereas in basophils, alpha-tryptases predominant. TPSG1 differs from other members of the tryptase gene family in that it has C-terminal hydrophobic domain, which may serve as a membrane anchor. Tryptases have been implicated as mediators in the pathogenesis of asthma and other allergic and inflammatory disorders.
Full Name
Tryptase Gamma 1
Biological Process
Biological Process proteolysis Source:GO_Central1 Publication
Cellular Location
Membrane
Topology
Helical: 284-304
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Anti-TPSG1 antibodies

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Target: TPSG1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYJT-4428
Application*: WB
Target: TPSG1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYJT-4427
Application*: WB
Target: TPSG1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYJT-4426
Application*: WB
Target: TPSG1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYJT-4425
Application*: WB
Target: TPSG1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYJT-4424
Application*: WB, IF, F
Target: TPSG1
Host: Rat
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBYJT-4423
Application*: WB, IP
Target: TPSG1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYJT-4422
Application*: WB, F, IH, P
Target: TPSG1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYJT-4421
Application*: WB, F
Target: TPSG1
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBYJT-4420
Application*: WB, F
Target: TPSG1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Dog, Cat, Human, Monkey, Rat
Clone: CBFYM-3165
Application*: E, IF, IH, WB
More Infomation
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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