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Mouse Anti-TPSG1 Recombinant Antibody (CBFYM-3165) (CBMAB-M3362-FY)

This product is mouse antibody that recognizes TPSG1. The antibody CBFYM-3165 can be used for immunoassay techniques such as: ELISA, IF, IHC, WB.
See all TPSG1 antibodies

Summary

Host Animal
Mouse
Specificity
Dog, Cat, Human, Monkey, Rat
Clone
CBFYM-3165
Antibody Isotype
IgG1
Application
ELISA, IF, IHC, WB

Basic Information

Immunogen
Human mast cell tryptase purified from human lung tissue
Specificity
Dog, Cat, Human, Monkey, Rat
Antibody Isotype
IgG1
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS
Preservative
0.09% Sodium azide
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Tryptase Gamma 1
Introduction
Tryptases comprise a family of trypsin-like serine proteases, the peptidase family S1. Tryptases are enzymatically active only as heparin-stabilized tetramers, and they are resistant to all known endogenous proteinase inhibitors. Several tryptase genes are clustered on chromosome 16p13.3. There is uncertainty regarding the number of genes in this cluster. Currently four functional genes - alpha I, beta I, beta II and gamma I - have been identified. And beta I has an allelic variant named alpha II, beta II has an allelic variant beta III, also gamma I has an allelic variant gamma II. Beta tryptases appear to be the main isoenzymes expressed in mast cells; whereas in basophils, alpha-tryptases predominant. This gene differs from other members of the tryptase gene family in that it has C-terminal hydrophobic domain, which may serve as a membrane anchor. Tryptases have been implicated as mediators in the pathogenesis of asthma and other allergic and inflammatory disorders.
Entrez Gene ID
Human25823
Monkey100425751
Rat302990
UniProt ID
HumanQ9NRR2
MonkeyF6X5Q3
RatQ80XZ3
Alternative Names
Tryptase Gamma 1; Transmembrane Tryptase; Serine Protease 31; Tryptase Gamma II; Tryptase Gamma I; PRSS31
Biological Process
Biological Process proteolysis Source:GO_Central1 Publication
Cellular Location
Membrane
Topology
Helical: 284-304
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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