TRA2B

TRA2B is a nuclear protein which plays a role as sequence-specific serine/arginine splicing factor which plays a role in mRNA processing, splicing patterns, and gene expression.
Full Name
Transformer 2 Beta Homolog
Function
Sequence-specific RNA-binding protein which participates in the control of pre-mRNA splicing. Can either activate or suppress exon inclusion. Acts additively with RBMX to promote exon 7 inclusion of the survival motor neuron SMN2. Activates the splicing of MAPT/Tau exon 10. Alters pre-mRNA splicing patterns by antagonizing the effects of splicing regulators, like RBMX. Binds to the AG-rich SE2 domain in the SMN exon 7 RNA. Binds to pre-mRNA.
Biological Process
Biological Process cellular response to glucose stimulus Source:CAFA1 Publication
Biological Process cerebral cortex regionalization Source:Ensembl
Biological Process embryonic brain development Source:Ensembl
Biological Process mRNA splicing, via spliceosome Source:UniProtKB1 Publication
Biological Process positive regulation of mRNA splicing, via spliceosome Source:UniProtKB1 Publication
Biological Process regulation of alternative mRNA splicing, via spliceosome Source:UniProtKB2 Publications
Biological Process regulation of RNA splicing Source:UniProtKB1 Publication
Biological Process RNA splicing, via transesterification reactions Source:UniProtKB1 Publication
Cellular Location
Nucleus
PTM
Phosphorylated in the RS domains.
Dimethylation at Arg-241 is probably asymmetric.
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Anti-TRA2B antibodies

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Mouse Anti-TRA2B Recombinant Antibody (7A1) (CBMAB-A8032-LY)

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Target: TRA2B
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: 7A1
Application*: WB, E
Datasheet SDS

Mouse Anti-TRA2B Recombinant Antibody (CBYJT-4473) (CBMAB-T3976-YJ)

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Target: TRA2B
Host: Mouse
Antibody Isotype: IgG
Specificity: Human, Rat, Mouse
Clone: CBYJT-4473
Application*: WB, IP, IF, E
Datasheet SDS

Mouse Anti-TRA2B Recombinant Antibody (CBYJT-4472) (CBMAB-T3975-YJ)

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Target: TRA2B
Host: Mouse
Antibody Isotype: IgG
Specificity: Human, Rat, Mouse
Clone: CBYJT-4472
Application*: WB, IP, IF, P, E
Datasheet SDS

Mouse Anti-TRA2B Recombinant Antibody (CBYJT-4471) (CBMAB-T3974-YJ)

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Target: TRA2B
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBYJT-4471
Application*: E, WB
Datasheet SDS
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Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized) Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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