TRA2B

TRA2B is a nuclear protein which plays a role as sequence-specific serine/arginine splicing factor which plays a role in mRNA processing, splicing patterns, and gene expression.

Transformer 2 Beta Homolog

Sequence-specific RNA-binding protein which participates in the control of pre-mRNA splicing. Can either activate or suppress exon inclusion. Acts additively with RBMX to promote exon 7 inclusion of the survival motor neuron SMN2. Activates the splicing of MAPT/Tau exon 10. Alters pre-mRNA splicing patterns by antagonizing the effects of splicing regulators, like RBMX. Binds to the AG-rich SE2 domain in the SMN exon 7 RNA. Binds to pre-mRNA.

Biological Process cellular response to glucose stimulus Source:CAFA1 Publication
Biological Process cerebral cortex regionalization Source:Ensembl
Biological Process embryonic brain development Source:Ensembl
Biological Process mRNA splicing, via spliceosome Source:UniProtKB1 Publication
Biological Process positive regulation of mRNA splicing, via spliceosome Source:UniProtKB1 Publication
Biological Process regulation of alternative mRNA splicing, via spliceosome Source:UniProtKB2 Publications
Biological Process regulation of RNA splicing Source:UniProtKB1 Publication
Biological Process RNA splicing, via transesterification reactions Source:UniProtKB1 Publication

Nucleus

Phosphorylated in the RS domains.
Dimethylation at Arg-241 is probably asymmetric.