TTF2
This gene encodes a member of the SWI2/SNF2 family of proteins, which play a critical role in altering protein-DNA interactions. The encoded protein has been shown to have dsDNA-dependent ATPase activity and RNA polymerase II termination activity. This protein interacts with cell division cycle 5-like, associates with human splicing complexes, and plays a role in pre-mRNA splicing. [provided by RefSeq]
Full Name
transcription termination factor, RNA polymerase II
Function
DsDNA-dependent ATPase which acts as a transcription termination factor by coupling ATP hydrolysis with removal of RNA polymerase II from the DNA template. May contribute to mitotic transcription repression. May also be involved in pre-mRNA splicing.
Biological Process
Biological Process DNA repair Source:GO_Central1 Publication
Biological Process DNA-templated transcription termination Source:ProtInc1 Publication
Biological Process mRNA processing Source:UniProtKB-KW
Biological Process RNA splicing Source:UniProtKB-KW
Biological Process termination of RNA polymerase II transcription Source:ProtInc1 Publication
Biological Process DNA-templated transcription termination Source:ProtInc1 Publication
Biological Process mRNA processing Source:UniProtKB-KW
Biological Process RNA splicing Source:UniProtKB-KW
Biological Process termination of RNA polymerase II transcription Source:ProtInc1 Publication
Cellular Location
Cytoplasm
Nucleus
Cytoplasmic during interphase. Relocates to the nucleus as cells enter mitosis.
Nucleus
Cytoplasmic during interphase. Relocates to the nucleus as cells enter mitosis.
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Anti-TTF2 antibodies
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Target: TTF2
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: 3F7
Application*: WB, E
Target: TTF2
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: 3D11
Application*: WB, E
Target: TTF2
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human, Mouse, Rat
Clone: 2B6
Application*: WB, E
Target: TTF2
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human, Rat
Clone: 1E8
Application*: WB, E
Target: TTF2
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human, Rat, Mouse
Clone: CBYJT-5153
Application*: WB, P, F, IC, IF
Target: TTF2
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human, Rat
Clone: CBYJT-5152
Application*: E, WB
Target: TTF2
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: CBYJT-5151
Application*: WB, IP, IF, E
Target: TTF2
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: CBYJT-5150
Application*: E, WB
Target: TTF2
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: CBYJT-5149
Application*: E, WB
Target: TTF2
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: CBYJT-5148
Application*: E, IF, WB
Target: TTF2
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: CBYJT-5147
Application*: E, WB
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IGImmunochromatography
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot
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