Mouse Anti-TTF2 Recombinant Antibody (CBYJT-5150) (CBMAB-T4728-YJ)

Name: Mouse Anti-TTF2 Recombinant Antibody (CBYJT-5150)
SKU: CBMAB-T4728-YJ
Rating: 5 (1 reviews)

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Datasheet

SDS

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Basic Information

Host Animal

Mouse

Clone

CBYJT-5150

Application

ELISA, WB

Immunogen

TTF2 (NP_003585, 385aa-509aa) full length recombinant protein with GST tag. MW of the GST tag alone is 26kD

Specificity

Human

Antibody Isotype

IgG

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Buffer

PBS, pH 7.4

Storage

Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Epitope

aa 385-509

More Infomation

Target

Full Name

transcription termination factor, RNA polymerase II

Introduction

TTF2 is a member of the SWI2/SNF2 family of proteins, which play a critical role in altering protein-DNA interactions. TTF2 has been shown to have dsDNA-dependent ATPase activity and RNA polymerase II termination activity. TTF2 interacts with cell division cycle 5-like, associates with human splicing complexes, and plays a role in pre-mRNA splicing.

Entrez Gene ID

8458

UniProt ID

Q9UNY4

Alternative Names

Transcription Termination Factor 2; Transcription Release Factor 2; Transcription Termination Factor, RNA Polymerase II; RNA Polymerase II Termination Factor; Zinc Finger, GRF-Type Containing 6; Lodestar Homolog; HuF2

Function

DsDNA-dependent ATPase which acts as a transcription termination factor by coupling ATP hydrolysis with removal of RNA polymerase II from the DNA template. May contribute to mitotic transcription repression. May also be involved in pre-mRNA splicing.

Biological Process

Biological Process DNA repair Source:GO_Central1 Publication
Biological Process DNA-templated transcription termination Source:ProtInc1 Publication
Biological Process mRNA processing Source:UniProtKB-KW
Biological Process RNA splicing Source:UniProtKB-KW
Biological Process termination of RNA polymerase II transcription Source:ProtInc1 Publication

Cellular Location

Cytoplasm
Nucleus
Cytoplasmic during interphase. Relocates to the nucleus as cells enter mitosis.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

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Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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