UBE2F

Accepts the ubiquitin-like protein NEDD8 from the UBA3-NAE1 E1 complex and catalyzes its covalent attachment to other proteins. The specific interaction with the E3 ubiquitin ligase RBX2, but not RBX1, suggests that the RBX2-UBE2F complex neddylates specific target proteins, such as CUL5.
Full Name
Ubiquitin Conjugating Enzyme E2 F (Putative)
Function
Accepts the ubiquitin-like protein NEDD8 from the UBA3-NAE1 E1 complex and catalyzes its covalent attachment to other proteins. The specific interaction with the E3 ubiquitin ligase RBX2, but not RBX1, suggests that the RBX2-UBE2F complex neddylates specific target proteins, such as CUL5.
Biological Process
Biological Process post-translational protein modification Source:Reactome
Biological Process protein neddylation Source:UniProtKB1 Publication
Cellular Location
cytosol
nucleus
PTM
The acetylation of Met-1 increases affinity for DCUN1D3 by about 2 orders of magnitude and is crucial for NEDD8 transfer to cullins.
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Anti-UBE2F antibodies

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Rabbit Anti-UBE2F Recombinant Antibody (CBWJN-1700) (CBMAB-N4349-WJ)

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Target: UBE2F
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: CBWJN-1700
Application*: WB, P, F, IC
Datasheet SDS

Human Recombinant UBE2F protein, His Tag-1 (V2LY-0526-LY7495)

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Target: UBE2F
Expressed Host: E. coli
Sequence: Amino Acid: 1-185
Tag: His Tag
Datasheet SDS

Human Recombinant UBE2F protein, His Tag (V2LY-0526-LY7494)

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Target: UBE2F
Expressed Host: E. coli
Sequence: Amino Acid: Full Length
Tag: His Tag
Datasheet SDS

Mouse Anti-UBE2F Recombinant Antibody (CBFYU-102) (CBMAB-U0102-FY)

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Target: UBE2F
Host: Mouse
Specificity: Mouse, Rat, Human
Clone: CBFYU-102
Application*: WB, IP, IF, E
Datasheet SDS
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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