ULBP2

This gene encodes a major histocompatibility complex (MHC) class I-related molecule that binds to the NKG2D receptor on natural killer (NK) cells to trigger release of multiple cytokines and chemokines that in turn contribute to the recruitment and activation of NK cells. The encoded protein undergoes further processing to generate the mature protein that is either anchored to membrane via a glycosylphosphatidylinositol moiety, or secreted. Many malignant cells secrete the encoded protein to evade immunosurveillance by NK cells. This gene is located in a cluster of multiple MHC class I-related genes on chromosome 6. [provided by RefSeq, Jul 2015]
Full Name
UL16 Binding Protein 2
Function
Binds and activates the KLRK1/NKG2D receptor, mediating natural killer cell cytotoxicity.
Biological Process
Biological Process natural killer cell activation Source:UniProtKB1 Publication
Biological Process natural killer cell mediated cytotoxicity Source:UniProtKB1 Publication
Cellular Location
Cell membrane
Endoplasmic reticulum
Secreted
In CMV-infected fibroblasts, detected in the endoplasmic reticulum/cis-Golgi.
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Anti-ULBP2 antibodies

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Human Recombinant ULBP2 protein, His Tag (V2LY-0526-LY7534)

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Target: ULBP2
Expressed Host: HEK293 Cells
Sequence: Amino Acid: 1-217
Tag: His Tag
Datasheet SDS

Human Recombinant ULBP2 protein, Biotin Conjugated, His & AVI Tag (V2LY-0526-LY7533)

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Target: ULBP2
Expressed Host: HEK293 Cells
Sequence: Amino Acid: 1-217
Tag: His & AVI Tag
Datasheet SDS

Human Recombinant ULBP2 protein, hFc Tag (V2LY-0526-LY7532)

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Target: ULBP2
Expressed Host: HEK293 Cells
Sequence: Amino Acid: 1-217
Tag: hFc Tag
Datasheet SDS

Mouse Anti-ULBP2 Recombinant Antibody (CBT4764) (V2LY-0625-LY1398)

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Target: ULBP2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBT4764
Application*: IC, F
Datasheet SDS

Mouse Anti-ULBP2 Recombinant Antibody (CBT3608) (V2LY-0625-LY1397)

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Target: ULBP2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBT3608
Application*: IC, F
Datasheet SDS

Mouse Anti-ULBP2 Recombinant Antibody (CBCNC-768) (CBMAB-C4592-CN)

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Target: ULBP2
Host: Mouse
Specificity: Human
Clone: CBCNC-768
Application*: E
Datasheet SDS

Mouse Anti-ULBP2 Recombinant Antibody (7F33) (CBMAB-C4590-CN)

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Target: ULBP2
Host: Mouse
Antibody Isotype: IgG2
Specificity: Human
Clone: 7F33
Application*: FC, N
Datasheet SDS

Mouse Anti-ULBP2 Recombinant Antibody (14L966) (CBMAB-C4589-CN)

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Target: ULBP2
Host: Mouse
Antibody Isotype: IgG2
Specificity: Human
Clone: 14L966
Application*: FC, N
Datasheet SDS

Rabbit Anti-ULBP2 Recombinant Antibody (010) (CBMAB-C4587-CN)

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Target: ULBP2
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: 010
Application*: WB
Datasheet SDS

Rabbit Anti-ULBP2 Recombinant Antibody (003) (CBMAB-C4586-CN)

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Target: ULBP2
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: 003
Application*: E
Datasheet SDS

Rabbit Anti-ULBP2 Recombinant Antibody (22) (CBMAB-A4938-YC)

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Target: ULBP2
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: 22
Application*: P
Datasheet SDS
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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