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Mouse Anti-ULBP2 Recombinant Antibody (7F33) (CBMAB-C4590-CN)

This product is a Mouse antibody that recognizes ULBP2. The antibody 7F33 can be used for immunoassay techniques such as: FC, Neut.
See all ULBP2 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
7F33
Antibody Isotype
IgG2
Application
FC, Neut

Basic Information

Immunogen
Human recombinant ULBP-2
Specificity
Human
Antibody Isotype
IgG2
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Lyophilized
Buffer
PBS

Target

Full Name
UL16 Binding Protein 2
Introduction
This gene encodes a major histocompatibility complex (MHC) class I-related molecule that binds to the NKG2D receptor on natural killer (NK) cells to trigger release of multiple cytokines and chemokines that in turn contribute to the recruitment and activation of NK cells. The encoded protein undergoes further processing to generate the mature protein that is either anchored to membrane via a glycosylphosphatidylinositol moiety, or secreted. Many malignant cells secrete the encoded protein to evade immunosurveillance by NK cells. This gene is located in a cluster of multiple MHC class I-related genes on chromosome 6. [provided by RefSeq, Jul 2015]
Entrez Gene ID
80328
UniProt ID
Q9BZM5
Alternative Names
UL16 Binding Protein 2; Retinoic Acid Early Transcript 1H; NKG2D Ligand 2; ALCAN-Alpha; NKG2DL2; RAET1H; N2DL2; UL16-Binding Protein 2; N2DL-2;
Function
Binds and activates the KLRK1/NKG2D receptor, mediating natural killer cell cytotoxicity.
Biological Process
Biological Process natural killer cell activation Source:UniProtKB1 Publication
Biological Process natural killer cell mediated cytotoxicity Source:UniProtKB1 Publication
Cellular Location
Cell membrane
Endoplasmic reticulum
Secreted
In CMV-infected fibroblasts, detected in the endoplasmic reticulum/cis-Golgi.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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