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UTRN

This gene shares both structural and functional similarities with the dystrophin gene. It contains an actin-binding N-terminus, a triple coiled-coil repeat central region, and a C-terminus that consists of protein-protein interaction motifs which interact with dystroglycan protein components. The protein encoded by this gene is located at the neuromuscular synapse and myotendinous junctions, where it participates in post-synaptic membrane maintenance and acetylcholine receptor clustering. Mouse studies suggest that this gene may serve as a functional substitute for the dystrophin gene and therefore, may serve as a potential therapeutic alternative to muscular dystrophy which is caused by mutations in the dystrophin gene. Alternative splicing of the utrophin gene has been described; however, the full-length nature of these variants has not yet been determined. [provided by RefSeq]
Full Name
utrophin
Function
May play a role in anchoring the cytoskeleton to the plasma membrane.
Biological Process
Biological Process actin cytoskeleton organization Source:GO_Central1 Publication
Biological Process muscle contraction Source:ProtInc1 Publication
Biological Process muscle organ development Source:ProtInc1 Publication
Biological Process positive regulation of cell-matrix adhesion Source:UniProtKB1 Publication
Biological Process regulation of sodium ion transmembrane transporter activity Source:BHF-UCLBy Similarity
Cellular Location
Postsynaptic cell membrane
Cytoplasm, cytoskeleton
Neuromuscular junction.

Anti-UTRN antibodies

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Mouse Anti-UTRN Antibody (10D4) (CBMAB-1791CQ)

Datasheet SDS
Target: UTRN
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: 10D4
Application*: WB

Mouse Anti-UTRN Antibody (6A10) (CBMAB-1792CQ)

Datasheet SDS
Target: UTRN
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 6A10
Application*: WB

Mouse Anti-UTRN Antibody (10A7) (CBMAB-1793CQ)

Datasheet SDS
Target: UTRN
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: 10A7
Application*: WB

Mouse Anti-UTRN Antibody (7C11) (CBMAB-1794CQ)

Datasheet SDS
Target: UTRN
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 7C11
Application*: WB

Mouse Anti-UTRN (aa 768-874) Recombinant Antibody (CBXU-007) (CBMAB-U0124-CQ)

Datasheet SDS
Target: UTRN
Host: Mouse
Antibody Isotype: IgG1
Specificity: Mouse
Clone: CBXU-007
Application*: WB

Mouse Anti-UTRN Antibody (9E10) (CBMAB-1771CQ)

Datasheet SDS
Target: UTRN
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 9E10
Application*: WB, IF

Mouse Anti-UTRN Antibody (9F2) (CBMAB-1772CQ)

Datasheet SDS
Target: UTRN
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Fish, Mouse
Clone: 9F2
Application*: IF, WB

Mouse Anti-UTRN Antibody (2G12) (CBMAB-1773CQ)

Datasheet SDS
Target: UTRN
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 2G12
Application*: IF, WB

Mouse Anti-UTRN Antibody (40) (CBMAB-1774CQ)

Datasheet SDS
Target: UTRN
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 40
Application*: IF, WB

Mouse Anti-UTRN Antibody (4C8) (CBMAB-1775CQ)

Datasheet SDS
Target: UTRN
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human, Common fruit fly, Fish, Mouse
Clone: 4C8
Application*: IF, WB

Mouse Anti-UTRN Antibody (3C1) (CBMAB-1776CQ)

Datasheet SDS
Target: UTRN
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human, Fish, Mouse, Frog
Clone: 3C1
Application*: IF, WB

Mouse Anti-UTRN Antibody (9G3) (CBMAB-1777CQ)

Datasheet SDS
Target: UTRN
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Dog, Mouse, Frog
Clone: 9G3
Application*: WB, IF

Mouse Anti-UTRN Antibody (8A4) (CBMAB-1778CQ)

Datasheet SDS
Target: UTRN
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Dog, Mouse, Frog
Clone: 8A4
Application*: IF, IH, WB

Mouse Anti-UTRN Antibody (2G5) (CBMAB-1779CQ)

Datasheet SDS
Target: UTRN
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Dog, Mouse, Frog
Clone: 2G5
Application*: IF, IH, WB

Mouse Anti-UTRN Antibody (7F3) (CBMAB-1780CQ)

Datasheet SDS
Target: UTRN
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human, Mouse
Clone: 7F3
Application*: IF, IH, WB

Mouse Anti-UTRN Antibody (3B6) (CBMAB-1781CQ)

Datasheet SDS
Target: UTRN
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 3B6
Application*: WB, IF

Mouse Anti-UTRN Antibody (3B3) (CBMAB-1782CQ)

Datasheet SDS
Target: UTRN
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 3B3
Application*: WB

Mouse Anti-UTRN Antibody (4B12) (CBMAB-1783CQ)

Datasheet SDS
Target: UTRN
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: 4B12
Application*: WB

Mouse Anti-UTRN Antibody (2A5) (CBMAB-1784CQ)

Datasheet SDS
Target: UTRN
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: 2A5
Application*: WB

Mouse Anti-UTRN Antibody (8A3) (CBMAB-1785CQ)

Datasheet SDS
Target: UTRN
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: 8A3
Application*: WB

Mouse Anti-UTRN Antibody (5E10) (CBMAB-1786CQ)

Datasheet SDS
Target: UTRN
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: 5E10
Application*: WB

Mouse Anti-UTRN Antibody (5C9) (CBMAB-1787CQ)

Datasheet SDS
Target: UTRN
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: 5C9
Application*: WB

Mouse Anti-UTRN Antibody (4E3) (CBMAB-1788CQ)

Datasheet SDS
Target: UTRN
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: 4E3
Application*: WB

Mouse Anti-UTRN Antibody (6H4) (CBMAB-1789CQ)

Datasheet SDS
Target: UTRN
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: 6H4
Application*: WB

Mouse Anti-UTRN Antibody (8C11) (CBMAB-1790CQ)

Datasheet SDS
Target: UTRN
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 8C11
Application*: WB

Mouse Anti-UTRN Recombinant Antibody (5G6) (CBMAB-U0101-CQ)

Datasheet SDS
Target: UTRN
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: 5G6
Application*: E, IF, WB
For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
IFImmunofluorescence
IHImmunohistochemistry
IPImmunoprecipitation
WBWestern Blot
EELISA
MMicroarray
CIChromatin Immunoprecipitation
FFlow Cytometry
FNFunction Assay
IDImmunodiffusion
RRadioimmunoassay
TCTissue Culture
GSGel Supershift
NNeutralization
BBlocking
AActivation
IInhibition
DDepletion
ESELISpot
DBDot Blot
MCMass Cytometry/CyTOF
CTCytotoxicity
SStimulation
AGAgonist
APApoptosis
IMImmunomicroscopy
BABioassay
CSCostimulation
EMElectron Microscopy
IEImmunoelectrophoresis
PAPeptide Array
ICImmunocytochemistry
PEPeptide ELISA
MDMeDIP
SHIn situ hybridization
IAEnzyme Immunoassay
SEsandwich ELISA
PLProximity Ligation Assay
ECELISA(Cap)
EDELISA(Det)
BIBioimaging
IOImmunoassay
LFLateral Flow Immunoassay
LALuminex Assay
CImmunohistochemistry-Frozen Sections
PImmunohistologyp-Paraffin Sections
ISIntracellular Staining for Flow Cytometry
MSElectrophoretic Mobility Shift Assay
RIRNA Binding Protein Immunoprecipitation (RIP)
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