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Mouse Anti-UTRN Antibody (9E10) (CBMAB-1771CQ)

This product is a mouse antibody that recognizes UTRN. The antibody 9E10 can be used for immunoassay techniques such as: WB, IF.
See all UTRN antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
9E10
Antibody Isotype
IgG1
Application
WB, IF

Basic Information

Specificity
Human
Antibody Isotype
IgG1
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Supernatant
Purity
>95% as determined by analysis by SDS-PAGE
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
utrophin
Introduction
This gene shares both structural and functional similarities with the dystrophin gene. It contains an actin-binding N-terminus, a triple coiled-coil repeat central region, and a C-terminus that consists of protein-protein interaction motifs which interact with dystroglycan protein components. The protein encoded by this gene is a component of the cytoskeleton. Utrophin was found during research into Duchenne's muscular dystrophy. Diseases associated with UTRN include Becker Muscular Dystrophy and Duchenne Muscular Dystrophy. Among its related pathways are Primary Focal Segmental Glomerulosclerosis FSGS and Agrin Interactions at Neuromuscular Junction.
Entrez Gene ID
7402
UniProt ID
P46939
Alternative Names
DRP; DMDL; DRP1
Function
May play a role in anchoring the cytoskeleton to the plasma membrane.
Biological Process
Biological Process actin cytoskeleton organization Source:GO_Central1 Publication
Biological Process muscle contraction Source:ProtInc1 Publication
Biological Process muscle organ development Source:ProtInc1 Publication
Biological Process positive regulation of cell-matrix adhesion Source:UniProtKB1 Publication
Biological Process regulation of sodium ion transmembrane transporter activity Source:BHF-UCLBy Similarity
Cellular Location
Postsynaptic cell membrane
Cytoplasm, cytoskeleton
Neuromuscular junction.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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