VPS8

VPS8 (VPS8, CORVET Complex Subunit) is a Protein Coding gene. Gene Ontology (GO) annotations related to this gene include binding.
Full Name
VPS8, CORVET Complex Subunit
Function
Plays a role in vesicle-mediated protein trafficking of the endocytic membrane transport pathway. Believed to act as a component of the putative CORVET endosomal tethering complexes which is proposed to be involved in the Rab5-to-Rab7 endosome conversion probably implicating MON1A/B, and via binding SNAREs and SNARE complexes to mediate tethering and docking events during SNARE-mediated membrane fusion. The CORVET complex is proposed to function as a Rab5 effector to mediate early endosome fusion probably in specific endosome subpopulations (PubMed:25266290).
Functions predominantly in APPL1-containing endosomes (PubMed:25266290).
Biological Process
Biological Process endosomal vesicle fusion Source:UniProtKB1 Publication
Biological Process protein transport Source:UniProtKB-KW
Biological Process regulation of SNARE complex assembly Source:ComplexPortal1 Publication
Cellular Location
Early endosome
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Anti-VPS8 antibodies

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Mouse Anti-VPS8 Recombinant Antibody (2C8) (CBMAB-A4678-LY)

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Target: VPS8
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human
Clone: 2C8
Application*: WB, E
Datasheet SDS

Mouse Anti-VPS8 Recombinant Antibody (2C8) (CBMAB-V0055-YC)

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Target: VPS8
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human
Clone: 2C8
Application*: E, WB
Datasheet SDS
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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