Mouse Anti-VPS8 Recombinant Antibody (2C8) (CBMAB-V0055-YC)

Name: Mouse Anti-VPS8 Recombinant Antibody (2C8)
SKU: CBMAB-V0055-YC
Rating: 5 (1 reviews)

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Datasheet

SDS

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Basic Information

Host Animal

Mouse

Clone

2C8

Application

ELISA, WB

Immunogen

KIAA0804 (NP_001009921, aa 1329-1429) partial recombinant protein with GST tag.

Specificity

Human

Antibody Isotype

IgG2b, Κ

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage

Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Epitope

aa 1329-1429

More Infomation

Target

Full Name

VPS8, CORVET Complex Subunit

Introduction

VPS8 is a protein coding gene. Gene Ontology (GO) annotations show that VPS8 is related to binding.

Entrez Gene ID

23355

UniProt ID

Q8N3P4

Alternative Names

VPS8, CORVET Complex Subunit; KIaa 0804; Vacuolar Protein Sorting-Associated Protein 8 Homolog; Vacuolar Protein Sorting 8 Homolog (S. Cerevisiae); Vacuolar Protein Sorting 8 Homolog

Function

Plays a role in vesicle-mediated protein trafficking of the endocytic membrane transport pathway. Believed to act as a component of the putative CORVET endosomal tethering complexes which is proposed to be involved in the Rab5-to-Rab7 endosome conversion probably implicating MON1A/B, and via binding SNAREs and SNARE complexes to mediate tethering and docking events during SNARE-mediated membrane fusion. The CORVET complex is proposed to function as a Rab5 effector to mediate early endosome fusion probably in specific endosome subpopulations (PubMed:25266290).
Functions predominantly in APPL1-containing endosomes (PubMed:25266290).

Biological Process

Biological Process endosomal vesicle fusion Source:UniProtKB1 Publication
Biological Process protein transport Source:UniProtKB-KW
Biological Process regulation of SNARE complex assembly Source:ComplexPortal1 Publication

Cellular Location

Early endosome

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Alternative Versions

Mouse Anti-VPS8 Recombinant Antibody (2C8) (CAT#: CBMAB-A4678-LY)

Related Products

Mouse Anti-VPS8 Recombinant Antibody (2C8) (CAT#: CBMAB-A4678-LY)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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