WDR66

WDR66 is a protein-coding gene encodes the protein which belongs to the WD repeat-containing family of proteins and function in the formation of protein-protein complexes in a variety of biological pathways. Gene Ontology (GO) annotations related to this gene include calcium ion binding.
Full Name
WD repeat domain 66
Function
Involved in spermatozoa motility (PubMed:30122540, PubMed:30122541).
May also regulate cilium motility through its role in the assembly of the axonemal radial spokes (By similarity).
Biological Process
Biological Process cilium movement Source:UniProtKB
Biological Process flagellated sperm motility Source:UniProtKB1 Publication
Cellular Location
Cytoplasm, cytoskeleton, cilium axoneme
Cell projection, cilium, flagellum
Involvement in disease
Spermatogenic failure 33 (SPGF33):
An autosomal recessive infertility disorder caused by spermatogenesis defects that result in multiple abnormalities of sperm flagellum, including short, bent, curled, thick, or absent flagella.
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Anti-WDR66 antibodies

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Mouse Anti-WDR66 Recombinant Antibody (CBT2098) (V2LY-0625-LY19)

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Target: WDR66
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBT2098
Application*: F
Datasheet SDS

Mouse Anti-WDR66 Recombinant Antibody (2A6F7) (CBMAB-W0065-WJ)

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Target: WDR66
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 2A6F7
Application*: WB, F, E, MC
Datasheet SDS

Mouse Anti-WDR66 Recombinant Antibody (CBWJW-203) (CBMAB-W0022-WJ)

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Target: WDR66
Host: Mouse
Specificity: Human
Clone: CBWJW-203
Application*: E, F, WB
Datasheet SDS
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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