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WDR66

WDR66 is a protein-coding gene encodes the protein which belongs to the WD repeat-containing family of proteins and function in the formation of protein-protein complexes in a variety of biological pathways. Gene Ontology (GO) annotations related to this gene include calcium ion binding.

Full Name

WD repeat domain 66

Function

Involved in spermatozoa motility (PubMed:30122540, PubMed:30122541).
May also regulate cilium motility through its role in the assembly of the axonemal radial spokes (By similarity).

Biological Process

Biological Process cilium movement Source:UniProtKB
Biological Process flagellated sperm motility Source:UniProtKB1 Publication

Cellular Location

Cytoplasm, cytoskeleton, cilium axoneme
Cell projection, cilium, flagellum

Involvement in disease

Spermatogenic failure 33 (SPGF33):
An autosomal recessive infertility disorder caused by spermatogenesis defects that result in multiple abnormalities of sperm flagellum, including short, bent, curled, thick, or absent flagella.

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Anti-WDR66 antibodies

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Mouse Anti-WDR66 Recombinant Antibody (CBT2098) (V2LY-0625-LY19)

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Target: WDR66

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: CBT2098

Application*: F

Mouse Anti-WDR66 Recombinant Antibody (2A6F7) (CBMAB-W0065-WJ)

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Target: WDR66

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: 2A6F7

Application*: WB, F, E, MC

Mouse Anti-WDR66 Recombinant Antibody (CBWJW-203) (CBMAB-W0022-WJ)

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Target: WDR66

Host: Mouse

Specificity: Human

Clone: CBWJW-203

Application*: E, F, WB

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Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized)

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Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized)

Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

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(P): Predicted

* Abbreviations

AActivation
AGAgonist
APApoptosis
BBlocking
BABioassay
BIBioimaging
CImmunohistochemistry-Frozen Sections
CIChromatin Immunoprecipitation
CTCytotoxicity
CSCostimulation
DDepletion
DBDot Blot

EELISA
ECELISA(Cap)
EDELISA(Det)
ESELISpot
EMElectron Microscopy
FFlow Cytometry
FNFunction Assay
GSGel Supershift
IInhibition
IAEnzyme Immunoassay
ICImmunocytochemistry
IDImmunodiffusion
IEImmunoelectrophoresis

IFImmunofluorescence
IGImmunochromatography
IHImmunohistochemistry
IMImmunomicroscopy
IOImmunoassay
IPImmunoprecipitation
ISIntracellular Staining for Flow Cytometry
LALuminex Assay
LFLateral Flow Immunoassay
MMicroarray
MCMass Cytometry/CyTOF
MDMeDIP

MSElectrophoretic Mobility Shift Assay
NNeutralization
PImmunohistologyp-Paraffin Sections
PAPeptide Array
PEPeptide ELISA
PLProximity Ligation Assay
RRadioimmunoassay
SStimulation
SESandwich ELISA
SHIn situ hybridization
TCTissue Culture
WBWestern Blot

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