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Mouse Anti-WDR66 Recombinant Antibody (CBWJW-203) (CBMAB-W0022-WJ)


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Summary

Host Animal
Mouse
Specificity
Human
Clone
CBWJW-203
Application
ELISA, FC, WB

Basic Information

Immunogen
Recombinant protein corresponding to aa1-250 from human WDR66 expressed in E. coli.
Specificity
Human
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Concentration
1 mg/mL
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
WD repeat domain 66
Introduction
WDR66 is a protein-coding gene encodes the protein which belongs to the WD repeat-containing family of proteins and function in the formation of protein-protein complexes in a variety of biological pathways. Gene Ontology (GO) annotations related to this gene include calcium ion binding.
Entrez Gene ID
144406
UniProt ID
Q8TBY9
Alternative Names
CFAP251; CaM-IP4
Function
Involved in spermatozoa motility (PubMed:30122540, PubMed:30122541).
May also regulate cilium motility through its role in the assembly of the axonemal radial spokes (By similarity).
Biological Process
Biological Process cilium movement Source:UniProtKB
Biological Process flagellated sperm motility Source:UniProtKB1 Publication
Cellular Location
Cytoplasm, cytoskeleton, cilium axoneme
Cell projection, cilium, flagellum
Involvement in disease
Spermatogenic failure 33 (SPGF33):
An autosomal recessive infertility disorder caused by spermatogenesis defects that result in multiple abnormalities of sperm flagellum, including short, bent, curled, thick, or absent flagella.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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