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Mouse Anti-WDR66 Recombinant Antibody (CBT2098) (V2LY-0625-LY19)


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Summary

Host Animal
Mouse
Specificity
Human
Clone
CBT2098
Antibody Isotype
IgG1
Application
FC

Basic Information

Immunogen
Purified recombinant fragment of human WDR66 (AA: 1-250) expressed in E. Coli.
Host Species
Mouse
Specificity
Human
Antibody Isotype
IgG1
Clonality
Monoclonal Antibody
Application Notes
ApplicationNote
WB1:500-1:2,000
FC1:200-1:400
ELISA1:10,000

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS
Preservative
Sodium azide
Concentration
Batch dependent
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
WD repeat domain 66
Entrez Gene ID
144406
Function
Involved in spermatozoa motility (PubMed:30122540, PubMed:30122541).
May also regulate cilium motility through its role in the assembly of the axonemal radial spokes (By similarity).
Biological Process
Biological Process cilium movement Source:UniProtKB
Biological Process flagellated sperm motility Source:UniProtKB1 Publication
Cellular Location
Cytoplasm, cytoskeleton, cilium axoneme
Cell projection, cilium, flagellum
Involvement in disease
Spermatogenic failure 33 (SPGF33):
An autosomal recessive infertility disorder caused by spermatogenesis defects that result in multiple abnormalities of sperm flagellum, including short, bent, curled, thick, or absent flagella.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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