WDR74

WDR74 (WD Repeat Domain 74) is a Protein Coding gene.
Full Name
WD Repeat Domain 74
Function
Regulatory protein of the MTREX-exosome complex involved in the synthesis of the 60S ribosomal subunit (PubMed:26456651).
Participates in an early cleavage of the pre-rRNA processing pathway in cooperation with NVL (PubMed:29107693).
Required for blastocyst formation, is necessary for RNA transcription, processing and/or stability during preimplantation development (By similarity).
Biological Process
Biological Process blastocyst formation Source:UniProtKB
Biological Process ribosomal large subunit biogenesis Source:UniProtKB1 Publication
Biological Process RNA metabolic process Source:UniProtKB
Biological Process rRNA processing Source:UniProtKB1 Publication
Cellular Location
Nucleus, nucleolus
Nucleus
Nucleolar location depends on active PolI transcription of pre-rRNA.
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Anti-WDR74 antibodies

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Mouse Anti-WDR74 Recombinant Antibody (4F2) (CBMAB-W0116-WJ)

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Target: WDR74
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 4F2
Application*: WB
Datasheet SDS

Mouse Anti-WDR74 Recombinant Antibody (4B2) (CBMAB-W0108-WJ)

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Target: WDR74
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 4B2
Application*: P, WB
Datasheet SDS

Mouse Anti-WDR74 Recombinant Antibody (3D10) (CBMAB-W0092-WJ)

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Target: WDR74
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 3D10
Application*: WB
Datasheet SDS
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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