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Mouse Anti-WDR74 Recombinant Antibody (3D10) (CBMAB-W0092-WJ)

This product is a mouse antibody that recognizes WDR74. The antibody 3D10 can be used for immunoassay techniques such as: WB.
See all WDR74 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
3D10
Antibody Isotype
IgG1
Application
WB

Basic Information

Specificity
Human
Antibody Isotype
IgG1
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
WD Repeat Domain 74
Introduction
WDR74 (WD Repeat Domain 74) is a Protein Coding gene.
Entrez Gene ID
54663
UniProt ID
Q6RFH5
Alternative Names
WDR74; WD repeat domain 74
Function
Regulatory protein of the MTREX-exosome complex involved in the synthesis of the 60S ribosomal subunit (PubMed:26456651).
Participates in an early cleavage of the pre-rRNA processing pathway in cooperation with NVL (PubMed:29107693).
Required for blastocyst formation, is necessary for RNA transcription, processing and/or stability during preimplantation development (By similarity).
Biological Process
Biological Process blastocyst formation Source:UniProtKB
Biological Process ribosomal large subunit biogenesis Source:UniProtKB1 Publication
Biological Process RNA metabolic process Source:UniProtKB
Biological Process rRNA processing Source:UniProtKB1 Publication
Cellular Location
Nucleus, nucleolus
Nucleus
Nucleolar location depends on active PolI transcription of pre-rRNA.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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