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XPNPEP2

Aminopeptidase P is a hydrolase specific for N-terminal imido bonds, which are common to several collagen degradation products, neuropeptides, vasoactive peptides, and cytokines. Structurally, the enzyme is a member of the 'pita bread fold' family and occ
Full Name
X-Prolyl Aminopeptidase 2
Function
Membrane-bound metalloprotease which catalyzes the removal of a penultimate prolyl residue from the N-termini of peptides, such as Arg-Pro-Pro. May play a role in the metabolism of the vasodilator bradykinin.
Biological Process
Biological Process proteolysis Source:UniProtKB-KW
Cellular Location
Cell membrane
Involvement in disease
Angioedema induced by ACE inhibitors (AEACEI):
A potentially life-threatening side effect of ACE inhibitors that appears in a subset of patients taking these drugs for hypertension and cardiovascular disease treatment. AEACEI is characterized by swelling of the face, lips, tongue, and airway that can lead to suffocation and death if severe.
PTM
N-glycosylated.

Anti-XPNPEP2 antibodies

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Mouse Anti-XPNPEP2 Recombinant Antibody (CBYC-A1093) (CBMAB-A4944-YC)

Datasheet SDS
Target: XPNPEP2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYC-A1093
Application*: WB, IP, N

Rabbit Anti-XPNPEP2 Recombinant Antibody (014) (CBMAB-X0152-YC)

Datasheet SDS
Target: XPNPEP2
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: 014
Application*: E

Rabbit Anti-XPNPEP2 Recombinant Antibody (018) (CBMAB-X0153-YC)

Datasheet SDS
Target: XPNPEP2
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: 018
Application*: E

Rabbit Anti-XPNPEP2 Recombinant Antibody (020) (CBMAB-X0154-YC)

Datasheet SDS
Target: XPNPEP2
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: 020
Application*: P

Rabbit Anti-XPNPEP2 Recombinant Antibody (108) (CBMAB-X0155-YC)

Datasheet SDS
Target: XPNPEP2
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: 108
Application*: E

Mouse Anti-XPNPEP2 Recombinant Antibody (CBYCX-122) (CBMAB-X0156-YC)

Datasheet SDS
Target: XPNPEP2
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBYCX-122
Application*: E, IP, WB

Mouse Anti-XPNPEP2 Recombinant Antibody (CBYCX-123) (CBMAB-X0157-YC)

Datasheet SDS
Target: XPNPEP2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYCX-123
Application*: E, IP, N, WB

Mouse Anti-XPNPEP2 Recombinant Antibody (391118) (CBMAB-X0158-YC)

Datasheet SDS
Target: XPNPEP2
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: 391118
Application*: IP, WB

Mouse Anti-XPNPEP2 Recombinant Antibody (391131) (CBMAB-X0159-YC)

Datasheet SDS
Target: XPNPEP2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 391131
Application*: IP, N, WB
For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
IFImmunofluorescence
IHImmunohistochemistry
IPImmunoprecipitation
WBWestern Blot
EELISA
MMicroarray
CIChromatin Immunoprecipitation
FFlow Cytometry
FNFunction Assay
IDImmunodiffusion
RRadioimmunoassay
TCTissue Culture
GSGel Supershift
NNeutralization
BBlocking
AActivation
IInhibition
DDepletion
ESELISpot
DBDot Blot
MCMass Cytometry/CyTOF
CTCytotoxicity
SStimulation
AGAgonist
APApoptosis
IMImmunomicroscopy
BABioassay
CSCostimulation
EMElectron Microscopy
IEImmunoelectrophoresis
PAPeptide Array
ICImmunocytochemistry
PEPeptide ELISA
MDMeDIP
SHIn situ hybridization
IAEnzyme Immunoassay
SEsandwich ELISA
PLProximity Ligation Assay
ECELISA(Cap)
EDELISA(Det)
BIBioimaging
IOImmunoassay
LFLateral Flow Immunoassay
LALuminex Assay
CImmunohistochemistry-Frozen Sections
PImmunohistologyp-Paraffin Sections
ISIntracellular Staining for Flow Cytometry
MSElectrophoretic Mobility Shift Assay
RIRNA Binding Protein Immunoprecipitation (RIP)
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