XPNPEP2

Aminopeptidase P is a hydrolase specific for N-terminal imido bonds, which are common to several collagen degradation products, neuropeptides, vasoactive peptides, and cytokines. Structurally, the enzyme is a member of the 'pita bread fold' family and occ
Full Name
X-Prolyl Aminopeptidase 2
Function
Membrane-bound metalloprotease which catalyzes the removal of a penultimate prolyl residue from the N-termini of peptides, such as Arg-Pro-Pro. May play a role in the metabolism of the vasodilator bradykinin.
Biological Process
Biological Process proteolysis Source:UniProtKB-KW
Cellular Location
Cell membrane
Involvement in disease
Angioedema induced by ACE inhibitors (AEACEI):
A potentially life-threatening side effect of ACE inhibitors that appears in a subset of patients taking these drugs for hypertension and cardiovascular disease treatment. AEACEI is characterized by swelling of the face, lips, tongue, and airway that can lead to suffocation and death if severe.
PTM
N-glycosylated.
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Anti-XPNPEP2 antibodies

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Mouse Anti-XPNPEP2 Recombinant Antibody (CBYC-A1093) (CBMAB-A4944-YC)

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Target: XPNPEP2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYC-A1093
Application*: WB, IP, N
Datasheet SDS

Mouse Anti-XPNPEP2 Recombinant Antibody (391131) (CBMAB-X0159-YC)

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Target: XPNPEP2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 391131
Application*: IP, N, WB
Datasheet SDS

Mouse Anti-XPNPEP2 Recombinant Antibody (391118) (CBMAB-X0158-YC)

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Target: XPNPEP2
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: 391118
Application*: IP, WB
Datasheet SDS

Mouse Anti-XPNPEP2 Recombinant Antibody (CBYCX-123) (CBMAB-X0157-YC)

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Target: XPNPEP2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYCX-123
Application*: E, IP, N, WB
Datasheet SDS

Mouse Anti-XPNPEP2 Recombinant Antibody (CBYCX-122) (CBMAB-X0156-YC)

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Target: XPNPEP2
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBYCX-122
Application*: E, IP, WB
Datasheet SDS

Rabbit Anti-XPNPEP2 Recombinant Antibody (108) (CBMAB-X0155-YC)

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Target: XPNPEP2
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: 108
Application*: E
Datasheet SDS

Rabbit Anti-XPNPEP2 Recombinant Antibody (020) (CBMAB-X0154-YC)

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Target: XPNPEP2
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: 020
Application*: P
Datasheet SDS

Rabbit Anti-XPNPEP2 Recombinant Antibody (018) (CBMAB-X0153-YC)

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Target: XPNPEP2
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: 018
Application*: E
Datasheet SDS

Rabbit Anti-XPNPEP2 Recombinant Antibody (014) (CBMAB-X0152-YC)

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Target: XPNPEP2
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: 014
Application*: E
Datasheet SDS
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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