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Mouse Anti-XPNPEP2 Recombinant Antibody (CBYCX-123) (CBMAB-X0157-YC)

Provided herein is a Mouse monoclonal antibody against Human XPNPEP2. The antibody, clone CBYCX-123, can be used for immunoassay techniques, such as ELISA, IP, Neut, WB.
See all XPNPEP2 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBYCX-123
Antibody Isotype
IgG1
Application
ELISA, IP, Neut, WB

Basic Information

Immunogen
NS0-derived recombinant human rhAPP2
Specificity
Human
Antibody Isotype
IgG1
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
X-Prolyl Aminopeptidase 2
Introduction
XPNPEP2 is a membrane-bound metalloprotease which catalyzes the removal of a penultimate prolyl residue from the N-termini of peptides, such as Arg-Pro-Pro. XPNPEP2 may play a role in the metabolism of the vasodilator bradykinin.
Entrez Gene ID
7512
UniProt ID
O43895
Alternative Names
APP2; AEACEI
Function
Membrane-bound metalloprotease which catalyzes the removal of a penultimate prolyl residue from the N-termini of peptides, such as Arg-Pro-Pro. May play a role in the metabolism of the vasodilator bradykinin.
Biological Process
Biological Process proteolysis Source:UniProtKB-KW
Cellular Location
Cell membrane
Involvement in disease
Angioedema induced by ACE inhibitors (AEACEI):
A potentially life-threatening side effect of ACE inhibitors that appears in a subset of patients taking these drugs for hypertension and cardiovascular disease treatment. AEACEI is characterized by swelling of the face, lips, tongue, and airway that can lead to suffocation and death if severe.
PTM
N-glycosylated.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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