ZFYVE16

This gene encodes an endosomal protein that belongs to the FYVE zinc finger family of proteins. The encoded protein is thought to regulate membrane trafficking in the endosome. This protein functions as a scaffold protein in the transforming growth factor-beta signaling pathway and is involved in positive and negative feedback regulation of the bone morphogenetic protein signaling pathway. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]
Full Name
Zinc Finger FYVE-Type Containing 16
Function
May be involved in regulating membrane trafficking in the endosomal pathway. Overexpression induces endosome aggregation. Required to target TOM1 to endosomes.
Biological Process
Biological Process endosomal transport Source:UniProtKB1 Publication
Biological Process protein targeting to lysosome Source:UniProtKB1 Publication
Biological Process regulation of endocytosis Source:UniProtKB1 Publication
Biological Process signal transduction Source:UniProtKB1 Publication
Biological Process vesicle organization Source:UniProtKB1 Publication
Cellular Location
Cytoplasm
Early endosome membrane
Localized to early endosomes. Membrane-associated, probably via its association with phosphatidylinositol 3-phosphate (PI3P).
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Anti-ZFYVE16 antibodies

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Mouse Anti-ZFYVE16 Recombinant Antibody (2E2) (CBMAB-A10034-LY)

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Target: ZFYVE16
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human
Clone: 2E2
Application*: WB, E
Datasheet SDS

Mouse Anti-ZFYVE16 Recombinant Antibody (V2-53690) (CBMAB-Z0243-WJ)

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Target: ZFYVE16
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human
Clone: V2-53690
Application*: E, WB
Datasheet SDS

Mouse Anti-ZFYVE16 Recombinant Antibody (CBWJZ-138) (CBMAB-Z0242-WJ)

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Target: ZFYVE16
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human
Clone: CBWJZ-138
Application*: WB, SE, E
Datasheet SDS

ZFYVE16 Matched Antibody Pair (1314) (APMAB-1314LY)

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Target: ZFYVE16
Specificity: Human
Datasheet SDS

ZFYVE16 Matched Antibody Pair (1313) (APMAB-1313LY)

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Target: ZFYVE16
Specificity: Human
Datasheet SDS
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Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized) Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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