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ZMYM3

This gene is located on the X chromosome and is subject to X inactivation. It is highly conserved in vertebrates and most abundantly expressed in the brain. The encoded protein is a component of histone deacetylase-containing multiprotein complexes that function through modifying chromatin structure to keep genes silent. A chromosomal translocation (X;13) involving this gene is associated with X-linked cognitive disability. Several alternatively spliced transcript variants have been found for this gene.

Full Name

ZMYM3

Function

Plays a role in the regulation of cell morphology and cytoskeletal organization.

Biological Process

Biological Process cytoskeleton organization Source:UniProtKB1 Publication
Biological Process regulation of cell morphogenesis Source:UniProtKB1 Publication

Cellular Location

Nucleus

Involvement in disease

A chromosomal aberration involving ZMYM3 may be a cause of X-linked intellectual disability in Xq13.1. Translocation t(X;13)(q13.1;?).

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Anti-ZMYM3 antibodies

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Mouse Anti-ZMYM3 Recombinant Antibody (6D7) (CBMAB-0895-LY)

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Target: ZMYM3

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: 6D7

Application*: IP, M

Mouse Anti-ZMYM3 Recombinant Antibody (2C3) (CBMAB-0894-LY)

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Target: ZMYM3

Host: Mouse

Antibody Isotype: IgG2b

Specificity: Human

Clone: 2C3

Application*: IP, M

Mouse Anti-ZMYM3 Recombinant Antibody (2B9) (CBMAB-0893-LY)

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Target: ZMYM3

Host: Mouse

Antibody Isotype: IgG2a

Specificity: Human

Clone: 2B9

Application*: IP, M, WB

Mouse Anti-ZMYM3 Recombinant Antibody (1H3) (CBMAB-0892-LY)

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Target: ZMYM3

Host: Mouse

Antibody Isotype: IgG2a

Specificity: Human

Clone: 1H3

Application*: IP, M, WB

Mouse Anti-ZMYM3 Monoclonal Antibody (1C11) (CBMAB-0410-LY)

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Target: ZMYM3

Host: Mouse

Antibody Isotype: IgG2a

Specificity: Human

Clone: 1C11

Application*: IP, E

Mouse Anti-ZMYM3 Recombinant Antibody (CBWJZ-157) (CBMAB-Z0316-WJ)

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Target: ZMYM3

Host: Mouse

Antibody Isotype: IgG2b

Specificity: Human

Clone: CBWJZ-157

Application*: IP

Mouse Anti-ZMYM3 Recombinant Antibody (CBWJZ-156) (CBMAB-Z0315-WJ)

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Target: ZMYM3

Host: Mouse

Antibody Isotype: IgG2a

Specificity: Human

Clone: CBWJZ-156

Application*: CI, IF

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Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized)

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(P): Predicted

* Abbreviations

AActivation
AGAgonist
APApoptosis
BBlocking
BABioassay
BIBioimaging
CImmunohistochemistry-Frozen Sections
CIChromatin Immunoprecipitation
CTCytotoxicity
CSCostimulation
DDepletion
DBDot Blot

EELISA
ECELISA(Cap)
EDELISA(Det)
ESELISpot
EMElectron Microscopy
FFlow Cytometry
FNFunction Assay
GSGel Supershift
IInhibition
IAEnzyme Immunoassay
ICImmunocytochemistry
IDImmunodiffusion
IEImmunoelectrophoresis

IFImmunofluorescence
IGImmunochromatography
IHImmunohistochemistry
IMImmunomicroscopy
IOImmunoassay
IPImmunoprecipitation
ISIntracellular Staining for Flow Cytometry
LALuminex Assay
LFLateral Flow Immunoassay
MMicroarray
MCMass Cytometry/CyTOF
MDMeDIP

MSElectrophoretic Mobility Shift Assay
NNeutralization
PImmunohistologyp-Paraffin Sections
PAPeptide Array
PEPeptide ELISA
PLProximity Ligation Assay
RRadioimmunoassay
SStimulation
SESandwich ELISA
SHIn situ hybridization
TCTissue Culture
WBWestern Blot

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