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Mouse Anti-ZMYM3 Recombinant Antibody (CBWJZ-156) (CBMAB-Z0315-WJ)


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Summary

Host Animal
Mouse
Specificity
Human
Clone
CBWJZ-156
Antibody Isotype
IgG2a
Application
ChIP, IF

Basic Information

Specificity
Human
Antibody Isotype
IgG2a
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Target

Full Name
ZMYM3
Introduction
This gene is located on the X chromosome and is subject to X inactivation. It is highly conserved in vertebrates and most abundantly expressed in the brain. The encoded protein is a component of histone deacetylase-containing multiprotein complexes that function through modifying chromatin structure to keep genes silent. A chromosomal translocation (X;13) involving this gene is associated with X-linked cognitive disability. Several alternatively spliced transcript variants have been found for this gene. Plays a role in the regulation of cell morphology and cytoskeletal organization.
Entrez Gene ID
9203
UniProt ID
Q14202
Alternative Names
MYM; ZNF198L2; ZNF261
Function
Plays a role in the regulation of cell morphology and cytoskeletal organization.
Biological Process
Biological Process cytoskeleton organization Source:UniProtKB1 Publication
Biological Process regulation of cell morphogenesis Source:UniProtKB1 Publication
Cellular Location
Nucleus
Involvement in disease
A chromosomal aberration involving ZMYM3 may be a cause of X-linked intellectual disability in Xq13.1. Translocation t(X;13)(q13.1;?).
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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