ZNF384

This gene encodes a C2H2-type zinc finger protein, which may function as a transcription factor. This gene also contains long CAG trinucleotide repeats that encode consecutive glutamine residues. The protein appears to bind and regulate the promoters of the extracellular matrix genes MMP1, MMP3, MMP7 and COL1A1. Studies in mouse suggest that nuclear matrix transcription factors (NP/NMP4) may be part of a general mechanical pathway that couples cell construction and function during extracellular matrix remodeling. Alternative splicing results in multiple transcript variants. Recurrent rearrangements of this gene with the Ewing's sarcoma gene, EWSR1 on chromosome 22, or with the TAF15 gene on chromosome 17, or with the TCF3 (E2A) gene on chromosome 19, have been observed in acute leukemia. A related pseudogene has been identified on chromosome 7.
Full Name
ZNF384
Function
Transcription factor that binds the consensus DNA sequence [GC]AAAAA. Seems to bind and regulate the promoters of MMP1, MMP3, MMP7 and COL1A1 (By similarity).
Biological Process
Biological Process regulation of transcription by RNA polymerase II Source:GO_Central1 Publication
Cellular Location
Nucleus
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Anti-ZNF384 antibodies

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Mouse Anti-ZNF384 Recombinant Antibody (1C11) (CBMAB-0814-LY)

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Target: ZNF384
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: 1C11
Application*: IP, M
Datasheet SDS

Mouse Anti-ZNF384 Recombinant Antibody (1E8) (CBMAB-0815-LY)

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Target: ZNF384
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 1E8
Application*: IP, M
Datasheet SDS

Mouse Anti-ZNF384 Recombinant Antibody (3545C5a) (CBMAB-Z0543-WJ)

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Target: ZNF384
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 3545C5a
Application*: DB, IC, IF, WB
Datasheet SDS

Mouse Anti-ZNF384 Recombinant Antibody (CBWJZ-198) (CBMAB-Z0542-WJ)

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Target: ZNF384
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBWJZ-198
Application*: WB
Datasheet SDS
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Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized) Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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