ZNF81

This gene encodes a protein that likely functions as a transcription factor. The protein contains an N-terminal KRAB domain and several C2H2-type zinc finger motifs. Mutations in this gene cause an X-linked form of intellectual disability (MRX45). Microduplication of a region of chromosome X including this gene has also been associated with other forms of intellectual disability.

Full Name

zinc finger protein 81

Function

May be involved in transcriptional regulation.

Biological Process

Biological Process regulation of transcription by RNA polymerase II Source:GO_Central1 Publication

Cellular Location

Nucleus

Involvement in disease

A chromosomal aberration involving ZNF81 is found in a severe intellectual disability patient. Translocation t(X;9)(p11.23;q34.3).

Anti-ZNF81 antibodies

Mouse Anti-ZNF81 Recombinant Antibody (2C7) (CBMAB-0723-LY)

Datasheet

SDS

Target: ZNF81

Host: Mouse

Antibody Isotype: IgG2b

Specificity: Human

Clone: 2C7

Application*: IP, M, WB

Mouse Anti-ZNF81 Recombinant Antibody (2G2) (CBMAB-0724-LY)

Datasheet

SDS

Target: ZNF81

Host: Mouse

Antibody Isotype: IgG2b

Specificity: Human

Clone: 2G2

Application*: IP, M

Mouse Anti-ZNF81 Recombinant Antibody (CBWJZ-250) (CBMAB-Z0669-WJ)

Datasheet

SDS

Target: ZNF81

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: CBWJZ-250

Application*: WB

Mouse Anti-ZNF81 Recombinant Antibody (3G3) (CBMAB-Z0670-WJ)

Datasheet

SDS

Target: ZNF81

Host: Mouse

Antibody Isotype: IgG2b, κ

Specificity: Human

Clone: 3G3

Application*: E, WB

Mouse Anti-ZNF81 Recombinant Antibody (3426C1a) (CBMAB-Z0671-WJ)

Datasheet

SDS

Target: ZNF81

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: 3426C1a

Application*: WB, DB

For Research Use Only. Not For Clinical Use.

(P): Predicted

* Abbreviations

IFImmunofluorescence

IHImmunohistochemistry

IPImmunoprecipitation

WBWestern Blot

EELISA

MMicroarray

CIChromatin Immunoprecipitation

FFlow Cytometry

FNFunction Assay

IDImmunodiffusion

RRadioimmunoassay

TCTissue Culture

GSGel Supershift

NNeutralization

BBlocking

AActivation

IInhibition

DDepletion

ESELISpot

DBDot Blot

MCMass Cytometry/CyTOF

CTCytotoxicity

SStimulation

AGAgonist

APApoptosis

IMImmunomicroscopy

BABioassay

CSCostimulation

EMElectron Microscopy

IEImmunoelectrophoresis

PAPeptide Array

ICImmunocytochemistry

PEPeptide ELISA

MDMeDIP

SHIn situ hybridization

IAEnzyme Immunoassay

SEsandwich ELISA

PLProximity Ligation Assay

ECELISA(Cap)

EDELISA(Det)

BIBioimaging

IOImmunoassay

LFLateral Flow Immunoassay

LALuminex Assay

CImmunohistochemistry-Frozen Sections

PImmunohistologyp-Paraffin Sections

ISIntracellular Staining for Flow Cytometry

MSElectrophoretic Mobility Shift Assay

RIRNA Binding Protein Immunoprecipitation (RIP)