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TRIM21 Matched Antibody Pair (1274) (APMAB-1274LY)

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Specifications

ApplIcation
Sandwich ELISA
Specificity
Human
Capture Antibody
Rabbit anti-TRIM21 polyclonal antibody, 100 ug
Detection Antibody
Anti-TRIM21 Mouse monoclonal, IgG2a antibody, 20 ug
Dilutions
10 ng/ml-100 ng/ml
Format
Liquid
Storage
Aliquot and store at -20°Cor -80°C. Avoid freeze-thaw cycles.
Introduction
This gene encodes a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The encoded protein is part of the RoSSA ribonucleoprotein, which includes a single polypeptide and one of four small RNA molecules. The RoSSA particle localizes to both the cytoplasm and the nucleus. RoSSA interacts with autoantigens in patients with Sjogren syndrome and systemic lupus erythematosus. Alternatively spliced transcript variants for this gene have been described but the full-length nature of only one has been determined. [provided by RefSeq, Jul 2008]
Alternative Names
Tripartite Motif Containing 21; Sjogren Syndrome Antigen A1 (52kDa, Ribonucleoprotein Autoantigen SS-A/Ro); 52 KDa Ribonucleoprotein Autoantigen Ro/SS-A; RING-Type E3 Ubiquitin Transferase TRIM21; Tripartite Motif-Containing Protein 21; Sjoegren Syndrome Type A Antigen; RING Finger Protein 81; 52 KDa Ro Protein; Ro(SS-A); RNF81;
Entrez Gene ID
UniProt ID
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For research use only. Not intended for any clinical use.

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