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ABCC10 Matched Antibody Pair (001) (APMAB-001LY)

This antibody pair set can be used for detecting and quantifying protein level of human ABCC10.
See all ABCC10 antibodies

Specifications

ApplIcation
Sandwich ELISA
Specificity
Human
Capture Antibody
Rabbit anti-ABCC10 polyclonal antibody, 100 ug
Detection Antibody
Anti-ABCC10 Mouse polyclonal antibody, 20 ug
Dilutions
10 ng/ml-100 ng/ml
Format
Liquid
Storage
Aliquot and store at -20°Cor -80°C. Avoid freeze-thaw cycles.
Introduction
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, and White). This ABC full-transporter is a member of the MRP subfamily which is involved in multi-drug resistance. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Nov 2010]
Alternative Names
ATP Binding Cassette Subfamily C Member 10; ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 10; ATP-Binding Cassette Sub-Family C Member 10; SIMRP7; MRP7; Multidrug Resistance-Associated Protein 7; EST182763;
Entrez Gene ID
89845
UniProt ID
Q5T3U5

Wang, J. Q., Wang, B., Ma, L. Y., Shi, Z., Liu, H. M., Liu, Z., & Chen, Z. S. (2021). Enhancement of anticancer drug sensitivity in multidrug resistance cells overexpressing ATP-binding cassette (ABC) transporter ABCC10 by CP55, a synthetic derivative of 5-cyano-6-phenylpyrimidin. Experimental Cell Research, 112728.

Yang, Y., Ji, N., Cai, C. Y., Wang, J. Q., Lei, Z. N., Teng, Q. X., ... & Chen, Z. S. (2020). Modulating the function of ABCB1: in vitro and in vivo characterization of sitravatinib, a tyrosine kinase inhibitor. Cancer Communications, 40(7), 285-300.

Mao, X., He, Z., Zhou, F., Huang, Y., & Zhu, G. (2019). Prognostic significance and molecular mechanisms of adenosine triphosphate-binding cassette subfamily C members in gastric cancer. Medicine, 98(50).

Mesci, S., Marakli, S., Yazgan, B., & YILDIRIM, T. (2019). The effect of ATP-binding cassette (ABC) transporters in human cancers. International Journal of Science Letters, 1(1), 14-19.

Umérez Igartua, M. (2018). Mir-pharmacogenetics in childhood acute lymphoblastic leukemia treatment.

Zhao, H., Huang, Y., Shi, J., Dai, Y., Wu, L., & Zhou, H. (2018). ABCC10 plays a significant role in the transport of gefitinib and contributes to acquired resistance to gefitinib in NSCLC. Frontiers in pharmacology, 9, 1312.

Zhang, H., Patel, A., Wang, Y. J., Zhang, Y. K., Kathawala, R. J., Qiu, L. H., ... & Chen, Z. S. (2017). The BTK inhibitor ibrutinib (PCI-32765) overcomes paclitaxel resistance in ABCB1-and ABCC10-overexpressing cells and tumors. Molecular cancer therapeutics, 16(6), 1021-1030.

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For research use only. Not intended for any clinical use.

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