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Rat Anti-ADAM19 Recombinant Antibody (V2-179769) (CBMAB-A1131-YC)

Provided herein is a Rat monoclonal antibody against Mouse ADAM Metallopeptidase Domain 19. The antibody can be used for immunoassay techniques, such as WB.
See all ADAM19 antibodies

Summary

Host Animal
Rat
Specificity
Mouse
Clone
V2-179769
Antibody Isotype
IgG2
Application
WB

Basic Information

Immunogen
Mouse recombinant protein of ADAM19 ectodomain
Host Species
Rat
Specificity
Mouse
Antibody Isotype
IgG2
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.
ApplicationNote
WB1:500-1:1,000

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
PBS
Buffer
PBS
Preservative
None
Concentration
0.5 mg/ml
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
ADAM Metallopeptidase Domain 19
Introduction
ADAM19 is a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins and have been implicated in a variety of biological processes involvin
Entrez Gene ID
UniProt ID
Alternative Names
ADAM Metallopeptidase Domain 19; A Disintegrin And Metalloproteinase Domain 19 (Meltrin Beta); Metalloprotease And Disintegrin Dendritic Antigen Marker; Meltrin-Beta; ADAM 19; MADDAM; MLTNB;
Function
Participates in the proteolytic processing of beta-type neuregulin isoforms which are involved in neurogenesis and synaptogenesis, suggesting a regulatory role in glial cell. Also cleaves alpha-2 macroglobulin. May be involved in osteoblast differentiation and/or osteoblast activity in bone (By similarity).
Biological Process
Amyloid precursor protein catabolic process
Extracellular matrix organization
Membrane protein ectodomain proteolysis
Placenta development
Positive regulation of cell-cell adhesion mediated by cadherin
Positive regulation of gene expression
Protein processing
Cellular Location
Membrane
Topology
Extracellular: 203-699 aa
Helical: 700-720 aa
Cytoplasmic: 721-955 aa
PTM
The precursor is cleaved by a furin endopeptidase.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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