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Mouse Anti-ADAMTS4 Recombinant Antibody (10D5) (CBMAB-0029CQ)

This product is a mouse antibody that recognizes ADAMTS4. The antibody 10D5 can be used for immunoassay techniques such as: Neut, WB.
Host Species
Mouse
Application
Neut, WB
Immunogen
Human recombinant ADAMTS4
Antibody Isotype
IgG2
Specificity
Human
Clone
10D5
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Introduction
ADAMTS4 is a member of the large ADAMTS family of zinc-dependent proteases. For a general description of the ADAMTS gene family, see ADAMTS1. This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of this family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Pratta et al. (2003) studied the production of ADAMTS4 in monolayer chondrocytes, capsular fibroblasts, and cartilage. They concluded that ADAMTS4 is constitutively produced in these cells and this tissue, and that stimulation by interleukin-1 (147760, 147720) results in aggrecanase activation.
Alternative Name
ADAMTS4; ADAM metallopeptidase with thrombospondin type 1 motif 4; ADMP-1; ADAMTS-2; ADAMTS-4
Entrez Gene ID
UniProt ID
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For Research Use Only. Not For Clinical Use.
Cat CBMAB-0029CQ
Conjugates
Size
Price $
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Second antibody and isotype control