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Mouse Anti-ADGRE5 Recombinant Antibody (CBT2852) (V2LY-0625-LY1028)


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Summary

Host Animal
Mouse
Specificity
Human
Clone
CBT2852
Antibody Isotype
IgG2a
Application
IHC, FC

Basic Information

Immunogen
Purified recombinant fragment of human CD97 (AA: extra 419-552) expressed in E. Coli.
Host Species
Mouse
Specificity
Human
Antibody Isotype
IgG2a
Clonality
Monoclonal Antibody
Application Notes
ApplicationNote
WB1:500-1:2,000
IHC-P1:200-1:1,000
FC1:200-1:400
ELISA1:10,000

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS
Preservative
Sodium azide
Concentration
Batch dependent
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
Adhesion G Protein-Coupled Receptor E5
Entrez Gene ID
976
UniProt ID
P48960
Function
Receptor potentially involved in both adhesion and signaling processes early after leukocyte activation. Plays an essential role in leukocyte migration.
Biological Process
Adenylate cyclase-activating G protein-coupled receptor signaling pathway
Cell adhesion
Cell-cell signaling
Cell surface receptor signaling pathway
G protein-coupled receptor signaling pathway
Immune response
Inflammatory response
Neutrophil degranulation
Cellular Location
Cell membrane
Adhesion G protein-coupled receptor E5 subunit alpha: Extracellular space
Topology
Extracellular: 21-552 aa
Helical: 553-572 aa
Cytoplasmic: 573-581 aa
Helical: 582-601 aa
Extracellular: 602-620 aa
Helical: 621-642 aa
Cytoplasmic: 643-653 aa
Helical: 654-674 aa
Extracellular: 675-691 aa
Helical: 692-712 aa
Cytoplasmic: 713-739 aa
Helical: 740-760 aa
Extracellular: 761-766 aa
Helical: 767-789 aa
Cytoplasmic: 790-835 aa
PTM
Proteolytically cleaved into 2 subunits, an extracellular alpha subunit and a seven-transmembrane subunit.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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