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Mouse Anti-ADH1B Recombinant Antibody (V2-179892) (CBMAB-A1276-YC)

Provided herein is a Mouse monoclonal antibody against Human Alcohol Dehydrogenase 1B (Class I), Beta Polypeptide. The antibody can be used for immunoassay techniques, such as FC, IF, IHC, WB.
See all ADH1B antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
V2-179892
Antibody Isotype
IgG1
Application
IHC-F, IF, IHC, WB

Basic Information

Immunogen
Full length recombinant protein of human ADH1B (NP_000659) produced in HEK293T cell.
Host Species
Mouse
Specificity
Human
Antibody Isotype
IgG1
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.
ApplicationNote
WB1:2,000
IF(ICC)1:100
IHC1:150
FC1:100

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
PBS, pH 7.3, 1% BSA, 50% glycerol, 0.02% sodium azide
Buffer
PBS, pH7.3, 1% BSA, 50% glycerol
Preservative
0.02% sodium azide
Concentration
Batch dependent
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Alcohol Dehydrogenase 1B (Class I), Beta Polypeptide
Introduction
ADH1B is a member of the alcohol dehydrogenase family. Members of this enzyme family metabolize a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products. This encoded protein, con
Entrez Gene ID
125
UniProt ID
P00325
Alternative Names
Alcohol Dehydrogenase 1B (Class I), Beta Polypeptide; Alcohol Dehydrogenase Subunit Beta; EC 1.1.1.1; ADH2; Alcohol Dehydrogenase 2 (Class I), Beta Polypeptide; Epididymis Secretory Protein Li 117;
Function
Catalyzes the NAD-dependent oxidation of all-trans-retinol and its derivatives such as all-trans-4-hydroxyretinol and may participate in retinoid metabolism. In vitro can also catalyzes the NADH-dependent reduction of all-trans-retinal and its derivatives such as all-trans-4-oxoretinal. Catalyzes in the oxidative direction with higher efficiency. Has the same affinity for all-trans-4-hydroxyretinol and all-trans-4-oxoretinal.
Biological Process
Ethanol oxidation
Retinoic acid metabolic process
Retinoid metabolic process
Retinol metabolic process
Cellular Location
Cytoplasm
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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