Mouse Anti-ALDH3B1 Recombinant Antibody (1F2) (CBMAB-A2293-YC)

Name: Mouse Anti-ALDH3B1 Recombinant Antibody (1F2)
SKU: CBMAB-A2293-YC
Rating: 5 (1 reviews)

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Datasheet

SDS

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Basic Information

Host Animal

Mouse

Clone

1F2

Application

ELISA, IP

Immunogen

ALDH3B1 (AAH13584, 1 a.a. ~ 468 a.a) full-length recombinant protein with GST tag.

Host Species

Mouse

Specificity

Human

Antibody Isotype

IgG2b, κ

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Buffer

PBS, pH 7.4

Preservative

None

Concentration

Batch dependent

Storage

Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

More Infomation

Target

Full Name

aldehyde dehydrogenase 3 family, member B1

Introduction

ALDH3B1 is a member of the aldehyde dehydrogenase protein family. Aldehyde dehydrogenases are a family of isozymes that may play a major role in the detoxification of aldehydes generated by alcohol metabolism and lipid peroxidation. The encoded protein is

Entrez Gene ID

221

UniProt ID

P43353

Alternative Names

Aldehyde Dehydrogenase 3 Family Member B1; Aldehyde Dehydrogenase 7; Aldehyde Dehydrogenase 3B1; EC 1.2.1.5; ALDH7; Aldehyde Dehydrogenase 3 Family, Member B1; Aldehyde Dehydrogenase Family 3 Member B1; EC 1.2.1; ALDH4;

Function

Oxidizes medium and long chain saturated and unsaturated aldehydes (PubMed:17382292, PubMed:23721920). Metabolizes also benzaldehyde (PubMed:17382292). Low activity towards acetaldehyde and 3,4-dihydroxyphenylacetaldehyde (PubMed:17382292, PubMed:23721920). May not metabolize short chain aldehydes. Can use both NADP+ and NAD+ as electron acceptor (PubMed:17382292). May have a protective role against the cytotoxicity induced by lipid peroxidation (PubMed:17382292).

Biological Process

Alcohol metabolic process Source: ProtInc
Aldehyde catabolic process Source: MGI
Cellular response to oxidative stress Source: MGI
Ethanol catabolic process Source: UniProtKB-UniPathway
Lipid metabolic process Source: ProtInc
Neutrophil degranulation Source: Reactome
Sphingolipid biosynthetic process Source: Reactome

Cellular Location

Cell membrane. Primarily in the plasma membrane as well as in some punctate structures in the cytoplasm.

PTM

Dually lipidated in the C-terminus; prenylation occurs prior to, and is a prerequisite for palmitoylation. It is also required for activity towards long-chain substrates.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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