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Mouse Anti-ALDH3B1 Recombinant Antibody (1F2) (CBMAB-A2293-YC)

Provided herein is a Mouse monoclonal antibody against Human Aldehyde Dehydrogenase 3 Family Member B1. The antibody can be used for immunoassay techniques, such as ELISA, IP.
See all ALDH3B1 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
1F2
Antibody Isotype
IgG2b, κ
Application
ELISA, IP

Basic Information

Immunogen
ALDH3B1 (AAH13584, 1 a.a. ~ 468 a.a) full-length recombinant protein with GST tag.
Host Species
Mouse
Specificity
Human
Antibody Isotype
IgG2b, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, pH 7.4
Preservative
None
Concentration
Batch dependent
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
aldehyde dehydrogenase 3 family, member B1
Introduction
ALDH3B1 is a member of the aldehyde dehydrogenase protein family. Aldehyde dehydrogenases are a family of isozymes that may play a major role in the detoxification of aldehydes generated by alcohol metabolism and lipid peroxidation. The encoded protein is
Entrez Gene ID
UniProt ID
Alternative Names
Aldehyde Dehydrogenase 3 Family Member B1; Aldehyde Dehydrogenase 7; Aldehyde Dehydrogenase 3B1; EC 1.2.1.5; ALDH7; Aldehyde Dehydrogenase 3 Family, Member B1; Aldehyde Dehydrogenase Family 3 Member B1; EC 1.2.1; ALDH4;
Function
Oxidizes medium and long chain saturated and unsaturated aldehydes (PubMed:17382292, PubMed:23721920). Metabolizes also benzaldehyde (PubMed:17382292). Low activity towards acetaldehyde and 3,4-dihydroxyphenylacetaldehyde (PubMed:17382292, PubMed:23721920). May not metabolize short chain aldehydes. Can use both NADP+ and NAD+ as electron acceptor (PubMed:17382292). May have a protective role against the cytotoxicity induced by lipid peroxidation (PubMed:17382292).
Biological Process
Alcohol metabolic process Source: ProtInc
Aldehyde catabolic process Source: MGI
Cellular response to oxidative stress Source: MGI
Ethanol catabolic process Source: UniProtKB-UniPathway
Lipid metabolic process Source: ProtInc
Neutrophil degranulation Source: Reactome
Sphingolipid biosynthetic process Source: Reactome
Cellular Location
Cell membrane. Primarily in the plasma membrane as well as in some punctate structures in the cytoplasm.
PTM
Dually lipidated in the C-terminus; prenylation occurs prior to, and is a prerequisite for palmitoylation. It is also required for activity towards long-chain substrates.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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