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Mouse Anti-CARF Recombinant Antibody (2A3) (CBMAB-A0321-LY)

The product is antibody recognizes ALS2CR8. The antibody 2A3 immunoassay techniques such as: WB, ELISA.
See all CARF antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
2A3
Antibody Isotype
IgG2a, κ
Application
WB, ELISA

Basic Information

Immunogen
ALS2CR8 (NP_079020, 621 a.a. ~ 718 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Specificity
Human
Antibody Isotype
IgG2a, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
Calcium Responsive Transcription Factor
Entrez Gene ID
79800
UniProt ID
Q8N187
Alternative Names
CARF; DKFZp667N246; FLJ12675; FLJ21579; NYD-SP24
Function
Acts as a transcriptional activator that mediates the calcium- and neuron-selective induction of BDNF exon III transcription. Binds to the consensus calcium-response element CaRE1 5'-CTATTTCGAG-3' sequence.
Biological Process
Cellular response to calcium ion Source: UniProtKB
Cellular response to potassium ion Source: UniProtKB
Positive regulation of transcription from RNA polymerase II promoter in response to calcium ion Source: UniProtKB
Regulation of DNA-binding transcription factor activity Source: Ensembl
Regulation of transcription by RNA polymerase II Source: GO_Central
Cellular Location
Nucleus
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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