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Mouse Anti-ANGPTL6 Recombinant Antibody (3H8) (CBMAB-A2732-YC)

Provided herein is a Mouse monoclonal antibody against Human Angiopoietin Like 6. The antibody can be used for immunoassay techniques, such as ELISA, WB.
See all ANGPTL6 antibodies
Published Data
Fig.1 Immunoblot analysis of ARP5.
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Summary

Host Animal
Mouse
Specificity
Human
Clone
3H8
Antibody Isotype
IgG2a, κ
Application
ELISA, WB

Basic Information

Immunogen
ANGPTL6 (NP_114123, 211-300 aa) partial recombinant protein with GST tag.
Host Species
Mouse
Specificity
Human
Antibody Isotype
IgG2a, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, pH 7.4
Preservative
None
Concentration
Batch dependent
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
angiopoietin-like 6
Introduction
ANGPTL6 may play a role in the wound healing process. ANGPTL6 may promote epidermal proliferation, remodeling and regeneration and promote the chemotactic activity of endothelial cells and induce neovascularization. ANGPTL6 may counteract high-fat diet-in
Entrez Gene ID
83854
UniProt ID
Q8NI99
Alternative Names
Angiopoietin Like 6; Angiopoietin-Related Protein 5; Angiopoietin-Related Growth Factor; Angiopoietin-Like Protein 6; Arp5; AGF; Angiopoietin-Related Protein 6; Angiopoietin-Like 6;
Function
May play a role in the wound healing process. May promote epidermal proliferation, remodeling and regeneration. May promote the chemotactic activity of endothelial cells and induce neovascularization. May counteract high-fat diet-induced obesity and related insulin resistance through increased energy expenditure.
Biological Process
Angiogenesis Source: UniProtKB-KW
Cell differentiation Source: UniProtKB-KW
Cellular Location
Secreted

Qaddoumi, M. G., Alanbaei, M., Hammad, M. M., Al Khairi, I., Cherian, P., Channanath, A., ... & Abubaker, J. (2020). Investigating the role of myeloperoxidase and angiopoietin-like protein 6 in obesity and diabetes. Scientific reports, 10(1), 1-10.

Fan, K. C., Wu, H. T., Wei, J. N., Chuang, L. M., Hsu, C. Y., Yen, I., ... & Li, H. Y. (2020). Serum angiopoietin-like protein 6, risk of type 2 diabetes, and response to hyperglycemia: a prospective cohort study. The Journal of Clinical Endocrinology & Metabolism, 105(5), e1949-e1957.

Namkung, J., Sohn, J. H., Chang, J. S., Park, S. W., Kim, J. Y., Koh, S. B., ... & Park, K. S. (2019). Increased serum angiopoietin-like 6 ahead of metabolic syndrome in a prospective cohort study. Diabetes & metabolism journal, 43(4), 521-529.

Erkan, G., Muratoglu, S., Ercin, U., & Bilgihan, A. (2018). Angiopoietin-like protein 2 and angiopoietin-like protein 6 levels in patients with nonalcoholic fatty liver disease. Archives of medical science: AMS, 14(4), 781.

Kim, M. J., Namkung, J., Chang, J. S., Kim, S. J., Park, K. S., & Kong, I. D. (2018). Leptin regulates the expression of angiopoietin-like 6. Biochemical and biophysical research communications, 502(3), 397-402.

Sharma, V., Pangtey, G. S., Gupta, R., Rehan, H. S., & Gupta, L. K. (2017). Correlation of long-term glycemic control as measured by glycated hemoglobin with serum angiopoietin-like 6 protein levels in type 2 diabetes mellitus patients. Indian journal of pharmacology, 49(3), 250.

Cinkajzlova, A., Lacinova, Z., Klouckova, J., Kavalkova, P., Trachta, P., Kosak, M., ... & Haluzík, M. (2017). Angiopoietin-like protein 6 in patients with obesity, type 2 diabetes mellitus, and anorexia nervosa: The influence of very low-calorie diet, bariatric surgery, and partial realimentation. Endocrine research, 42(1), 22-30.

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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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