Sign in or Register   Sign in or Register
  |  

Mouse Anti-APIP Recombinant Antibody (CBFYM-0864) (CBMAB-M1011-FY)

This product is mouse antibody that recognizes APIP. The antibody CBFYM-0864 can be used for immunoassay techniques such as: FC, WB.
See all APIP antibodies
Published Data
Mouse Anti-APIP Recombinant Antibody (CBFYM-0864) in WB
Western blot analysis of the miRNA-transfected cells. Cell lysates were prepared two days after transfection. ...View More
Tran, P. X., Inoue, J., Harada, H., & Inazawa, J. (2022). Potential for reversing miR-634-mediated cytoprotective processes to improve efficacy of chemotherapy against oral squamous cell carcinoma. Molecular Therapy-Oncolytics, 24, 897-908.

Summary

Host Animal
Mouse
Specificity
Human, Mouse, Rat
Clone
CBFYM-0864
Antibody Isotype
IgG1, κ
Application
WB, IP, IF, ELISA

Basic Information

Immunogen
Amino acids 141-179 within an internal region of APIP of human origin.
Host Species
Mouse
Specificity
Human, Mouse, Rat
Antibody Isotype
IgG1, κ
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.
ApplicationNote
WB1:100-1:1,000
IP1-2 µg per 100-500 µg of total protein (1 ml of cell lysate)
IF(ICC)1:50-1:500
ELISA1:30-1:3,000

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, 0.1% gelatin
Preservative
< 0.1% sodium azide
Concentration
0.2 mg/ml
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
APAF1 Interacting Protein
Introduction
APIP is an APAF1 -interacting protein that acts as a negative regulator of ischemic/hypoxic injury.
Entrez Gene ID
51074
UniProt ID
Q96GX9
Alternative Names
APAF1 Interacting Protein; Methylthioribulose-1-Phosphate Dehydratase; MTRu-1-P Dehydratase; HAPIP; Probable Methylthioribulose-1-Phosphate Dehydratase; APAF1-Interacting Protein
Function
Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P). Functions in the methionine salvage pathway, which plays a key role in cancer, apoptosis, microbial proliferation and inflammation. May inhibit the CASP1-related inflammatory response (pyroptosis), the CASP9-dependent apoptotic pathway and the cytochrome c-dependent and APAF1-mediated cell death.
Biological Process
Apoptotic process Source: UniProtKB-KW
L-methionine salvage from methylthioadenosine Source: UniProtKB
L-methionine salvage from S-adenosylmethionine Source: UniProtKB-UniRule
Negative regulation of apoptotic process Source: UniProtKB
Protein homotetramerization Source: UniProtKB
Pyroptosis Source: UniProtKB
Regulation of ERK1 and ERK2 cascade Source: UniProtKB
Cellular Location
Cytoplasm
Ask a question We look forward to hearing from you.
0 reviews or Q&As

Purchasing FAQs
Technical FAQs

Loading...
Have you used Mouse Anti-APIP Recombinant Antibody (CBFYM-0864)?
Submit a review and get a Coupon or an Amazon gift card. 20% off Coupon $30 eGift Card
Submit a review
Loading...
For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Online Inquiry

Documents

Contact us

  • Tel: (USA)
  • (UK)
  • Fax:
  • Email:

Submit A Review

Go to
Compare