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Mouse Anti-APPBP2 Recombinant Antibody (CBYC-A714) (CBMAB-A3333-YC)


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Summary

Host Animal
Mouse
Specificity
Human
Clone
CBYC-A714
Antibody Isotype
IgG2a, κ
Application
ELISA, WB

Basic Information

Immunogen
APPBP2 (NP_006371, 486 a.a. ~ 585 a.a) partial recombinant protein with GST tag.
Host Species
Mouse
Specificity
Human
Antibody Isotype
IgG2a, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, pH 7.4
Preservative
None
Concentration
Batch dependent
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Amyloid Beta Precursor Protein Binding Protein 2
Introduction
APPBP2 interacts with microtubules and is functionally associated with beta-amyloid precursor protein transport and/or processing. The beta-amyloid precursor protein is a cell surface protein with signal-transducing properties, and it is thought to play a
Entrez Gene ID
10513
UniProt ID
Q92624
Alternative Names
Amyloid Beta Precursor Protein Binding Protein 2; Protein Interacting With APP Tail 1; Amyloid Beta Precursor Protein (Cytoplasmic Tail) Binding Protein 2; APP-BP2; PAT1; Amyloid Beta Precursor Protein (Cytoplasmic Tail)-Binding Protein 2;
Function
May play a role in intracellular protein transport. May be involved in the translocation of APP along microtubules toward the cell surface.
Biological Process
Intracellular protein transport Source: ProtInc
Intracellular transport Source: MGI
Cellular Location
Cytoskeleton; Nucleus; Membrane. Associated with membranes and microtubules.
PTM
Rapidly degraded by the proteasome upon overexpression of a C-terminal fragment of APP.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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