APPBP2

The protein encoded by this gene interacts with microtubules and is functionally associated with beta-amyloid precursor protein transport and/or processing. The beta-amyloid precursor protein is a cell surface protein with signal-transducing properties, and it is thought to play a role in the pathogenesis of Alzheimer's disease. The encoded protein may be involved in regulating cell death. This gene has been found to be highly expressed in breast cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]
Full Name
Amyloid Beta Precursor Protein Binding Protein 2
Function
May play a role in intracellular protein transport. May be involved in the translocation of APP along microtubules toward the cell surface.
Biological Process
Intracellular protein transport Source: ProtInc
Intracellular transport Source: MGI
Cellular Location
Cytoskeleton; Nucleus; Membrane. Associated with membranes and microtubules.
PTM
Rapidly degraded by the proteasome upon overexpression of a C-terminal fragment of APP.
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Anti-APPBP2 antibodies

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Mouse Anti-Appbp2 Recombinant Antibody (CBYC-P019) (CBMAB-P0069-YC)

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Target: Appbp2
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: CBYC-P019
Application*: WB, E, IP
Datasheet SDS

Mouse Anti-APPBP2 Recombinant Antibody (CBYC-A714) (CBMAB-A3333-YC)

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Target: APPBP2
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: CBYC-A714
Application*: E, WB
Datasheet SDS
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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