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Mouse Anti-ARL11 Recombinant Antibody (1E1) (CBMAB-A3571-YC)

Provided herein is a Mouse monoclonal antibody against Human ADP Ribosylation Factor Like GTPase 11. The antibody can be used for immunoassay techniques, such as FC, IF, WB.
See all ARL11 antibodies

Summary

Host Animal
Mouse
Specificity
Human, Mouse
Clone
1E1
Antibody Isotype
IgG1
Application
FC, IF, WB

Basic Information

Immunogen
Full length human recombinant protein of human ARL11 produced in HEk293T cell.
Specificity
Human, Mouse
Antibody Isotype
IgG1
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.
ApplicationNote
WB1:2,000
IF(ICC)1:100
FC1:100

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, pH 7.3, 1% BSA, 50% glycerol
Preservative
0.02% sodium azide
Concentration
Batch dependent
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
ADP Ribosylation Factor Like GTPase 11
Introduction
ARL11 is a tumor suppressor related to the ADP-ribosylation factor (ARF) family of proteins. The encoded protein may play a role in apoptosis in a caspase-dependent manner. Polymorphisms in this gene have been associated with some familial cancers.
Entrez Gene ID
115761
UniProt ID
Q969Q4
Alternative Names
ADP Ribosylation Factor Like GTPase 11; ADP-Ribosylation Factor-Like Tumor Suppressor Protein 1; ADP-Ribosylation Factor-Like Tumor Suppressor Gene 1; ARLTS1; ADP-Ribosylation Factor-Like Protein 11; ADP-Ribosylation Factor Like GTPase 11; ADP-Ribosylatio
Function
May play a role in apoptosis. May act as a tumor suppressor.
Biological Process
Intracellular protein transport Source: GO_Central
Vesicle-mediated transport Source: GO_Central
Cellular Location
Plasma membrane
Involvement in disease
Leukemia, chronic lymphocytic (CLL): A chronic leukemia in which functionally incompetent B-lymphocytes progressively accumulate in the bone marrow, blood, and lymphoid tissues. The clinical evolution of the disorder is heterogeneous, with some patients having indolent disease and others having aggressive disease and short survival.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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