ARL11

ARL11 is a tumor suppressor related to the ADP-ribosylation factor (ARF) family of proteins. The encoded protein may play a role in apoptosis in a caspase-dependent manner. Polymorphisms in this gene have been associated with some familial cancers.
Full Name
ADP Ribosylation Factor Like GTPase 11
Function
May play a role in apoptosis. May act as a tumor suppressor.
Biological Process
Intracellular protein transport Source: GO_Central
Vesicle-mediated transport Source: GO_Central
Cellular Location
Plasma membrane
Involvement in disease
Leukemia, chronic lymphocytic (CLL): A chronic leukemia in which functionally incompetent B-lymphocytes progressively accumulate in the bone marrow, blood, and lymphoid tissues. The clinical evolution of the disorder is heterogeneous, with some patients having indolent disease and others having aggressive disease and short survival.
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Anti-ARL11 antibodies

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Mouse Anti-ARL11 Recombinant Antibody (1E1) (CBMAB-A3571-YC)

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Target: ARL11
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Mouse
Clone: 1E1
Application*: FC, IF, WB
Datasheet SDS

Mouse Anti-ARL11 Recombinant Antibody (1A5) (CBMAB-A3570-YC)

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Target: ARL11
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 1A5
Application*: FC, IF, IH, WB
Datasheet SDS
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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