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ARL11

ARL11 is a tumor suppressor related to the ADP-ribosylation factor (ARF) family of proteins. The encoded protein may play a role in apoptosis in a caspase-dependent manner. Polymorphisms in this gene have been associated with some familial cancers.

Full Name

ADP Ribosylation Factor Like GTPase 11

Function

May play a role in apoptosis. May act as a tumor suppressor.

Biological Process

Intracellular protein transport Source: GO_Central
Vesicle-mediated transport Source: GO_Central

Cellular Location

Plasma membrane

Involvement in disease

Leukemia, chronic lymphocytic (CLL): A chronic leukemia in which functionally incompetent B-lymphocytes progressively accumulate in the bone marrow, blood, and lymphoid tissues. The clinical evolution of the disorder is heterogeneous, with some patients having indolent disease and others having aggressive disease and short survival.

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Anti-ARL11 antibodies

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Mouse Anti-ARL11 Recombinant Antibody (1E1) (CBMAB-A3571-YC)

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Target: ARL11

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human, Mouse

Clone: 1E1

Application*: FC, IF, WB

Mouse Anti-ARL11 Recombinant Antibody (1A5) (CBMAB-A3570-YC)

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Target: ARL11

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: 1A5

Application*: FC, IF, IH, WB

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Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized)

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Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized)

Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

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For Research Use Only. Not For Clinical Use.

(P): Predicted

* Abbreviations

AActivation
AGAgonist
APApoptosis
BBlocking
BABioassay
BIBioimaging
CImmunohistochemistry-Frozen Sections
CIChromatin Immunoprecipitation
CTCytotoxicity
CSCostimulation
DDepletion
DBDot Blot

EELISA
ECELISA(Cap)
EDELISA(Det)
ESELISpot
EMElectron Microscopy
FFlow Cytometry
FNFunction Assay
GSGel Supershift
IInhibition
IAEnzyme Immunoassay
ICImmunocytochemistry
IDImmunodiffusion
IEImmunoelectrophoresis

IFImmunofluorescence
IGImmunochromatography
IHImmunohistochemistry
IMImmunomicroscopy
IOImmunoassay
IPImmunoprecipitation
ISIntracellular Staining for Flow Cytometry
LALuminex Assay
LFLateral Flow Immunoassay
MMicroarray
MCMass Cytometry/CyTOF
MDMeDIP

MSElectrophoretic Mobility Shift Assay
NNeutralization
PImmunohistologyp-Paraffin Sections
PAPeptide Array
PEPeptide ELISA
PLProximity Ligation Assay
RRadioimmunoassay
SStimulation
SESandwich ELISA
SHIn situ hybridization
TCTissue Culture
WBWestern Blot

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