ARL11

ARL11 is a tumor suppressor related to the ADP-ribosylation factor (ARF) family of proteins. The encoded protein may play a role in apoptosis in a caspase-dependent manner. Polymorphisms in this gene have been associated with some familial cancers.

Full Name

ADP Ribosylation Factor Like GTPase 11

Function

May play a role in apoptosis. May act as a tumor suppressor.

Biological Process

Intracellular protein transport Source: GO_Central
Vesicle-mediated transport Source: GO_Central

Cellular Location

Plasma membrane

Involvement in disease

Leukemia, chronic lymphocytic (CLL): A chronic leukemia in which functionally incompetent B-lymphocytes progressively accumulate in the bone marrow, blood, and lymphoid tissues. The clinical evolution of the disorder is heterogeneous, with some patients having indolent disease and others having aggressive disease and short survival.

Anti-ARL11 antibodies

Mouse Anti-ARL11 Recombinant Antibody (1E1) (CBMAB-A3571-YC)

Datasheet

SDS

Target: ARL11

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human, Mouse

Clone: 1E1

Application*: FC, IF, WB

Mouse Anti-ARL11 Recombinant Antibody (1A5) (CBMAB-A3570-YC)

Datasheet

SDS

Target: ARL11

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: 1A5

Application*: FC, IF, IH, WB

For Research Use Only. Not For Clinical Use.

(P): Predicted

* Abbreviations

IFImmunofluorescence

IHImmunohistochemistry

IPImmunoprecipitation

WBWestern Blot

EELISA

MMicroarray

CIChromatin Immunoprecipitation

FFlow Cytometry

FNFunction Assay

IDImmunodiffusion

RRadioimmunoassay

TCTissue Culture

GSGel Supershift

NNeutralization

BBlocking

AActivation

IInhibition

DDepletion

ESELISpot

DBDot Blot

MCMass Cytometry/CyTOF

CTCytotoxicity

SStimulation

AGAgonist

APApoptosis

IMImmunomicroscopy

BABioassay

CSCostimulation

EMElectron Microscopy

IEImmunoelectrophoresis

PAPeptide Array

ICImmunocytochemistry

PEPeptide ELISA

MDMeDIP

SHIn situ hybridization

IAEnzyme Immunoassay

SEsandwich ELISA

PLProximity Ligation Assay

ECELISA(Cap)

EDELISA(Det)

BIBioimaging

IOImmunoassay

LFLateral Flow Immunoassay

LALuminex Assay

CImmunohistochemistry-Frozen Sections

PImmunohistologyp-Paraffin Sections

ISIntracellular Staining for Flow Cytometry

MSElectrophoretic Mobility Shift Assay

RIRNA Binding Protein Immunoprecipitation (RIP)