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Mouse Anti-ARMCX1 Recombinant Antibody (6E10) (CBMAB-A0488-LY)

The product is antibody recognizes ARMCX1. The antibody 6E10 immunoassay techniques such as: WB, ELISA.
See all ARMCX1 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
6E10
Antibody Isotype
IgG3, κ
Application
WB, ELISA

Basic Information

Immunogen
ARMCX1 (NP_057692, 188 a.a. ~ 295 a.a) partial recombinant protein with GST tag.
Specificity
Human
Antibody Isotype
IgG3, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, pH 7.4
Preservative
None
Concentration
Batch dependent
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
Armadillo Repeat Containing, X-Linked 1
Introduction
This gene encodes a member of the ALEX family of proteins and may play a role in tumor suppression. The encoded protein contains a potential N-terminal transmembrane domain and two Armadillo (arm) repeats. Other proteins containing the arm repeat are involved in development, maintenance of tissue integrity, and tumorigenesis. This gene is closely localized with other family members, including ALEX2 and ALEX3, on the X chromosome. [provided by RefSeq]
Entrez Gene ID
51309
UniProt ID
Q9P291
Alternative Names
ALEX1; DKFZp686P06199
Function
Regulates mitochondrial transport during axon regeneration. Increases the proportion of motile mitochondria by recruiting stationary mitochondria into the motile pool. Enhances mitochondria movement and neurite growth in both adult axons and embryonic neurons. Promotes neuronal survival and axon regeneration after nerve injury. May link mitochondria to the Trak1-kinesin motor complex via its interaction with MIRO1.
Biological Process
Hematopoietic stem cell homeostasis Source: Ensembl
Cellular Location
Mitochondrion; Mitochondrion outer membrane
Topology
Mitochondrial intermembrane: 1-6 aa
Helical: 7-29 aa
Cytoplasmic: 30-453 aa
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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