Mouse Anti-ARRB1 Recombinant Antibody (CBYC-A797) (CBMAB-A3670-YC)

ARRB1

Members of arrestin/beta-arrestin protein family are thought to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory si

Arrestin Beta 1; Non-Visual Arrestin-2; Arrestin 2; ARR1; Arrestin, Beta 1; Beta-Arrestin-1; Arrestin Beta-1; ARB1;

Activation of MAPK activity Source: Ensembl
Follicle-stimulating hormone signaling pathway Source: Ensembl
G protein-coupled receptor internalization Source: UniProtKB
G protein-coupled receptor signaling pathway Source: Reactome
Histone acetylation Source: GOC
Membrane organization Source: Reactome
Negative regulation of ERK1 and ERK2 cascade Source: Ensembl
Negative regulation of GTPase activity Source: Ensembl
Negative regulation of interleukin-6 production Source: UniProtKB
Negative regulation of interleukin-8 production Source: UniProtKB
Negative regulation of neuron apoptotic process Source: Ensembl
Negative regulation of NF-kappaB transcription factor activity Source: UniProtKB
Negative regulation of Notch signaling pathway Source: UniProtKB
Negative regulation of protein phosphorylation Source: Ensembl
Negative regulation of protein ubiquitination Source: UniProtKB
Platelet activation Source: Reactome
Positive regulation of cell population proliferation Source: Ensembl
Positive regulation of cysteine-type endopeptidase activity involved in apoptotic process Source: Ensembl
Positive regulation of ERK1 and ERK2 cascade Source: UniProtKB
Positive regulation of histone acetylation Source: BHF-UCL
Positive regulation of histone H4 acetylation Source: UniProtKB
Positive regulation of protein phosphorylation Source: UniProtKB
Positive regulation of protein ubiquitination Source: Ensembl
Positive regulation of receptor internalization Source: UniProtKB
Positive regulation of Rho protein signal transduction Source: UniProtKB
Positive regulation of smooth muscle cell apoptotic process Source: Ensembl
Positive regulation of transcription by RNA polymerase II Source: BHF-UCL
Post-Golgi vesicle-mediated transport Source: Reactome
Proteasome-mediated ubiquitin-dependent protein catabolic process Source: UniProtKB
Protein transport Source: UniProtKB-KW
Protein ubiquitination Source: UniProtKB
Regulation of transcription by RNA polymerase II Source: UniProtKB
Response to drug Source: Ensembl
Stress fiber assembly Source: UniProtKB
Ubiquitin-dependent protein catabolic process Source: UniProtKB

Nucleus; Cell membrane; Cytoplasm; Clathrin-coated pit; Pseudopodium; Cytoplasmic vesicle. Translocates to the plasma membrane and colocalizes with antagonist-stimulated GPCRs. The monomeric form is predominantly located in the nucleus. The oligomeric form is located in the cytoplasm. Translocates to the nucleus upon stimulation of OPRD1 (By similarity).