Sign in or Register   Sign in or Register
  |  

Mouse Anti-ATAD3B Recombinant Antibody (A-8) (CBMAB-A3838-YC)

Provided herein is a Mouse monoclonal antibody against Human ATPase Family, AAA Domain Containing 3B. The antibody can be used for immunoassay techniques, such as WB, IP, IF, ELISA.
See all ATAD3B antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
A-8
Antibody Isotype
IgM, κ
Application
WB, IP, IF, ELISA, IHC-P

Basic Information

Immunogen
Amino acids 598-615 near the C-terminus of ATAD3B of human origin.
Specificity
Human
Antibody Isotype
IgM, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.
ApplicationNote
WB1:100-1:1,000
IP1-2 µg per 100-500 µg of total protein (1 ml of cell lysate)
IF(ICC)1:50-1:500
ELISA1:100-1:1,000
IHC-P1:50-1:500

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, 0.1% gelatin
Preservative
< 0.1% sodium azide
Concentration
0.2 mg/ml
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
ATPase Family, AAA Domain Containing 3B
Introduction
ATAD3B is localized to the mitochondrial inner membrane, where it can bind to a highly-related protein, ATAD3A. ATAD3A appears to interact with matrix nucleoid complexes, and the encoded protein negatively regulates that interaction. This gene is expresse
Entrez Gene ID
83858
UniProt ID
Q5T9A4
Alternative Names
ATPase Family, AAA Domain Containing 3B; AAA-TOB3; TOB3; ATPase Family AAA Domain-Containing Protein 3B; AAA-ATPase TOB3; KIAA1273;
Function
May play a role in a mitochondrial network organization typical for stem cells, characterized by reduced mitochondrial metabolism, low mtDNA copies and fragmentated mitochondrial network. may act by suppressing ATAD3A function, interfering with ATAD3A interaction with matrix nucleoid complexes.
Biological Process
Mitochondrion organization Source: GO_Central
Neutrophil degranulation Source: Reactome
Cellular Location
Mitochondrion inner membrane. Has been found to co-purify with nucleoids (PubMed:22453275). Since it does not face the mitochondrial matrix, the association with nucleoids could be mediated by ATAD3A.
Topology
Mitochondrial intermembrane: 2-246 aa
Helical: 247-264 aa
Mitochondrial intermembrane: 265-648 aa
Ask a question We look forward to hearing from you.
0 reviews or Q&As

Purchasing FAQs
Technical FAQs

Loading...
Have you used Mouse Anti-ATAD3B Recombinant Antibody (A-8)?
Submit a review and get a Coupon or an Amazon gift card. 20% off Coupon $30 eGift Card
Submit a review
Loading...
For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Online Inquiry

Documents

Contact us

  • Tel: (USA)
  • (UK)
  • Fax:
  • Email:

Submit A Review

Go to
Compare