Mouse Anti-AUP1 Recombinant Antibody (CBT4577) (V2LY-0625-LY1054)
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Basic Information
| Application | Note |
| WB | 1:500-1:2,000 |
| ELISA | 1:10,000 |
Formulations & Storage [For reference only, actual COA shall prevail!]
Target
Plays a role in lipid droplet formation (PubMed:21857022).
Induces lipid droplet clustering (PubMed:24039768).
Recruits ubiquitin-conjugating enzyme UBE2G2 to lipid droplets which facilitates its interaction with ubiquitin ligases AMFR/gp78 and RNF139/TRC8, leading to sterol-induced ubiquitination of HMGCR and its subsequent proteasomal degradation (PubMed:23223569, PubMed:21127063).
Also required for the degradation of INSIG1, SREBF1 and SREBF2 (PubMed:23223569).
Plays a role in regulating assembly and secretion of very low density lipoprotein particles and stability of apolipoprotein APOB (PubMed:28183703).
(Microbial infection) Following Dengue virus infection, required for induction of lipophagy which facilitates production of virus progeny particles.
Lipid droplet formation Source: UniProtKB
Lipid droplet organization Source: UniProtKB
Lipophagy Source: UniProtKB
Protein localization to lipid droplet Source: UniProtKB
Response to virus Source: UniProtKB
Retrograde protein transport, ER to cytosol Source: ParkinsonsUK-UCL
Ubiquitin-dependent ERAD pathway Source: UniProtKB
Viral process Source: UniProtKB-KW
Intramembrane: 21-41 aa
Cytoplasmic: 42-410 aa
(Microbial infection) Not ubiquitinated following Dengue virus infection.
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Please try the standard protocols which include: protocols, troubleshooting and guide.
Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols
Custom Antibody Labeling
We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).
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