Mouse Anti-AVEN Recombinant Antibody (EG321) (CBMAB-EN356-LY)

Name: Mouse Anti-AVEN Recombinant Antibody (EG321)
SKU: CBMAB-EN356-LY
Rating: 5 (1 reviews)

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Datasheet

SDS

Request for COA

Datasheet Target References Q & As Review & reward Protocols Associated Products

Basic Information

Host Animal

Mouse

Clone

EG321

Application

WB, IP, IF

Immunogen

Amino acids 262-362 of AVEN of human origin.

Specificity

Human, Mouse, Rat, Dog

Antibody Isotype

IgG1, κ

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Application	Note
WB	1:100-1:1,000
IP	1-2 µg per 100-500 µg of total protein (1 ml of cell lysate)
IF(ICC)	1:50-1:500

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Buffer

PBS, 0.1% gelatin

Preservative

< 0.1% sodium azide

Concentration

0.2 mg/ml

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

More Infomation

Target

Full Name

Apoptosis And Caspase Activation Inhibitor

Introduction

Protects against apoptosis mediated by Apaf-1.

Entrez Gene ID

57099

UniProt ID

Q9NQS1

Alternative Names

Apoptosis And Caspase Activation Inhibitor; Cell Death Regulator Aven; Programmed Cell Death 12; Apoptosis, Caspase Activation Inhibitor; PDCD12;

Function

Protects against apoptosis mediated by Apaf-1.

Biological Process

Apoptotic process Source: UniProtKB-KW
Negative regulation of apoptotic process Source: UniProtKB
Negative regulation of G2/M transition of mitotic cell cycle Source: GO_Central

Cellular Location

Endomembrane system. Associated with intracellular membranes.

Long, B., Wan, Y., Zhang, S., & Lv, L. (2020). LncRNA XIST protects podocyte from high glucose-induced cell injury in diabetic nephropathy by sponging miR-30 and regulating AVEN expression. Archives of Physiology and Biochemistry, 1-8.

Zhang, L., & Jia, X. (2019). Down-regulation of miR-30b-5p protects cardiomyocytes against hypoxia-induced injury by targeting Aven. Cellular & molecular biology letters, 24(1), 1-10.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols

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Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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