Mouse Anti-B3GNT2 Recombinant Antibody (CBYY-1886) (CBMAB-2235-YY)

Name: Mouse Anti-B3GNT2 Recombinant Antibody (CBYY-1886)
SKU: CBMAB-2235-YY
Rating: 5 (1 reviews)

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Datasheet

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Basic Information

Host Animal

Mouse

Clone

CBYY-1886

Application

WB, FC, IF

Immunogen

Full length human recombinant protein of human B3GNT2 produced in HEK293T cell.

Specificity

Human, Mouse, Rat

Antibody Isotype

IgG2a

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Application	Note
WB	1:1,000
IF(ICC)	1:100
FC	1:100

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Buffer

PBS, pH 7.3, 1% BSA, 50% glycerol

Preservative

0.02% sodium azide

Concentration

1 mg/ml

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

More Infomation

Target

Full Name

UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2

Introduction

This gene encodes a member of the beta-1,3-N-acetylglucosaminyltransferase family. This enzyme is a type II transmembrane protein. It prefers the substrate of lacto-N-neotetraose, and is involved in the biosynthesis of poly-N-acetyllactosamine chains. Two transcript variants encoding the same protein have been found for this gene.

Entrez Gene ID

10678

UniProt ID

Q9NY97

Alternative Names

UDP-GlcNAc:BetaGal Beta-1,3-N-Acetylglucosaminyltransferase 2; UDP-GlcNAc:BetaGal Beta-1,3-N-Acetylglucosaminyltransferase 1; Beta3Gn-T1; Beta3Gn-T2; B3GNT1; BGnT-2; UDP-Galactose:Beta-N-Acetylglucosamine Beta-1,3-Galactosyltransferase 7; N-Acetyllactosaminide Beta-1,3-N-Acetylglucosaminyltransferase 2; UDP-Gal:Beta-GlcNAc Beta-1,3-Galactosyltransferase 7; Beta-1,3-N-Acetylglucosaminyltransferase BGnT-1; Beta-1,3-N-Acetylglucosaminyltransferase BGnT-2; Beta-1,3-N-Acetylglucosaminyltransferase 1; Beta-1,3-N-Acetylglucosaminyltransferase 2; Beta-1,3-Galactosyltransferase 7; Beta-1,3-GalTase 7; Beta-1,3-Gn-T1; Beta-1,3-Gn-T2;

Function

Beta-1,3-N-acetylglucosaminyltransferase involved in the synthesis of poly-N-acetyllactosamine. Catalyzes the initiation and elongation of poly-N-acetyllactosamine chains. Shows a marked preference for Gal(beta1-4)Glc(NAc)-based acceptors (PubMed:9892646).
Probably constitutes the main polylactosamine synthase.

Biological Process

Axon guidance Source: Ensembl
Cellular response to leukemia inhibitory factor Source: Ensembl
Keratan sulfate biosynthetic process Source: Reactome
O-glycan processing Source: Reactome
Poly-N-acetyllactosamine biosynthetic process Source: UniProtKB
Protein glycosylation Source: GO_Central
Sensory perception of smell Source: Ensembl

Cellular Location

Golgi apparatus membrane

Topology

Cytoplasmic: 1-7 aa
Helical: 8-28 aa
Lumenal: 29-397 aa

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

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Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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