B3GNT2

This gene encodes a member of the beta-1,3-N-acetylglucosaminyltransferase family. This enzyme is a type II transmembrane protein. It prefers the substrate of lacto-N-neotetraose, and is involved in the biosynthesis of poly-N-acetyllactosamine chains. [provided by RefSeq]

Full Name

UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2

Function

Beta-1,3-N-acetylglucosaminyltransferase involved in the synthesis of poly-N-acetyllactosamine. Catalyzes the initiation and elongation of poly-N-acetyllactosamine chains. Shows a marked preference for Gal(beta1-4)Glc(NAc)-based acceptors (PubMed:9892646).
Probably constitutes the main polylactosamine synthase.

Biological Process

Axon guidance Source: Ensembl
Cellular response to leukemia inhibitory factor Source: Ensembl
Keratan sulfate biosynthetic process Source: Reactome
O-glycan processing Source: Reactome
Poly-N-acetyllactosamine biosynthetic process Source: UniProtKB
Protein glycosylation Source: GO_Central
Sensory perception of smell Source: Ensembl

Cellular Location

Golgi apparatus membrane

Topology

Cytoplasmic: 1-7 aa
Helical: 8-28 aa
Lumenal: 29-397 aa

Anti-B3GNT2 antibodies

Mouse Anti-B3GNT2 Recombinant Antibody (1A8) (CBMAB-A0686-LY)

Datasheet

SDS

Target: B3GNT2

Host: Mouse

Antibody Isotype: IgG2a, κ

Specificity: Human

Clone: 1A8

Application*: WB, E

Mouse Anti-B3GNT2 Recombinant Antibody (CBYY-1886) (CBMAB-2235-YY)

Datasheet

SDS

Target: B3GNT2

Host: Mouse

Antibody Isotype: IgG2a

Specificity: Human, Mouse, Rat

Clone: CBYY-1886

Application*: WB, FC, IF

Mouse Anti-B3GNT2 Recombinant Antibody (CBYY-0084) (CBMAB-0084-YY)

Datasheet

SDS

Target: B3GNT2

Host: Mouse

Antibody Isotype: IgG2b

Specificity: Human

Clone: CBYY-0084

Application*: WB

Mouse Anti-B3GNT2 Recombinant Antibody (CBYY-0083) (CBMAB-0083-YY)

Datasheet

SDS

Target: B3GNT2

Host: Mouse

Antibody Isotype: IgG2a

Specificity: Human, Mouse, Rat

Clone: CBYY-0083

Application*: WB, IH, IF

Mouse Anti-B3GNT2 Recombinant Antibody (CBYY-0082) (CBMAB-0082-YY)

Datasheet

SDS

Target: B3GNT2

Host: Mouse

Antibody Isotype: IgG2a

Specificity: Human, Mouse, Rat

Clone: CBYY-0082

Application*: IF, WB

Mouse Anti-B3GNT2 Recombinant Antibody (CBYY-0081) (CBMAB-0081-YY)

Datasheet

SDS

Target: B3GNT2

Host: Mouse

Antibody Isotype: IgG2a, κ

Specificity: Human

Clone: CBYY-0081

Application*: E, WB, IP

For Research Use Only. Not For Clinical Use.

(P): Predicted

* Abbreviations

IFImmunofluorescence

IHImmunohistochemistry

IPImmunoprecipitation

WBWestern Blot

EELISA

MMicroarray

CIChromatin Immunoprecipitation

FFlow Cytometry

FNFunction Assay

IDImmunodiffusion

RRadioimmunoassay

TCTissue Culture

GSGel Supershift

NNeutralization

BBlocking

AActivation

IInhibition

DDepletion

ESELISpot

DBDot Blot

MCMass Cytometry/CyTOF

CTCytotoxicity

SStimulation

AGAgonist

APApoptosis

IMImmunomicroscopy

BABioassay

CSCostimulation

EMElectron Microscopy

IEImmunoelectrophoresis

PAPeptide Array

ICImmunocytochemistry

PEPeptide ELISA

MDMeDIP

SHIn situ hybridization

IAEnzyme Immunoassay

SEsandwich ELISA

PLProximity Ligation Assay

ECELISA(Cap)

EDELISA(Det)

BIBioimaging

IOImmunoassay

LFLateral Flow Immunoassay

LALuminex Assay

CImmunohistochemistry-Frozen Sections

PImmunohistologyp-Paraffin Sections

ISIntracellular Staining for Flow Cytometry

MSElectrophoretic Mobility Shift Assay

RIRNA Binding Protein Immunoprecipitation (RIP)