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B3GNT2

This gene encodes a member of the beta-1,3-N-acetylglucosaminyltransferase family. This enzyme is a type II transmembrane protein. It prefers the substrate of lacto-N-neotetraose, and is involved in the biosynthesis of poly-N-acetyllactosamine chains. [provided by RefSeq]

Full Name

UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2

Function

Beta-1,3-N-acetylglucosaminyltransferase involved in the synthesis of poly-N-acetyllactosamine. Catalyzes the initiation and elongation of poly-N-acetyllactosamine chains. Shows a marked preference for Gal(beta1-4)Glc(NAc)-based acceptors (PubMed:9892646).
Probably constitutes the main polylactosamine synthase.

Biological Process

Axon guidance Source: Ensembl
Cellular response to leukemia inhibitory factor Source: Ensembl
Keratan sulfate biosynthetic process Source: Reactome
O-glycan processing Source: Reactome
Poly-N-acetyllactosamine biosynthetic process Source: UniProtKB
Protein glycosylation Source: GO_Central
Sensory perception of smell Source: Ensembl

Cellular Location

Golgi apparatus membrane

Topology

Cytoplasmic: 1-7 aa
Helical: 8-28 aa
Lumenal: 29-397 aa

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Anti-B3GNT2 antibodies

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Mouse Anti-B3GNT2 Recombinant Antibody (1A8) (CBMAB-A0686-LY)

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Target: B3GNT2

Host: Mouse

Antibody Isotype: IgG2a, κ

Specificity: Human

Clone: 1A8

Application*: WB, E

Mouse Anti-B3GNT2 Recombinant Antibody (CBYY-1886) (CBMAB-2235-YY)

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Target: B3GNT2

Host: Mouse

Antibody Isotype: IgG2a

Specificity: Human, Mouse, Rat

Clone: CBYY-1886

Application*: WB, FC, IF

Mouse Anti-B3GNT2 Recombinant Antibody (CBYY-0084) (CBMAB-0084-YY)

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Target: B3GNT2

Host: Mouse

Antibody Isotype: IgG2b

Specificity: Human

Clone: CBYY-0084

Application*: WB

Mouse Anti-B3GNT2 Recombinant Antibody (CBYY-0083) (CBMAB-0083-YY)

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Target: B3GNT2

Host: Mouse

Antibody Isotype: IgG2a

Specificity: Human, Mouse, Rat

Clone: CBYY-0083

Application*: WB, IH, IF

Mouse Anti-B3GNT2 Recombinant Antibody (CBYY-0082) (CBMAB-0082-YY)

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Target: B3GNT2

Host: Mouse

Antibody Isotype: IgG2a

Specificity: Human, Mouse, Rat

Clone: CBYY-0082

Application*: IF, WB

Mouse Anti-B3GNT2 Recombinant Antibody (CBYY-0081) (CBMAB-0081-YY)

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Target: B3GNT2

Host: Mouse

Antibody Isotype: IgG2a, κ

Specificity: Human

Clone: CBYY-0081

Application*: E, WB, IP

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Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized)

Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

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(P): Predicted

* Abbreviations

AActivation
AGAgonist
APApoptosis
BBlocking
BABioassay
BIBioimaging
CImmunohistochemistry-Frozen Sections
CIChromatin Immunoprecipitation
CTCytotoxicity
CSCostimulation
DDepletion
DBDot Blot

EELISA
ECELISA(Cap)
EDELISA(Det)
ESELISpot
EMElectron Microscopy
FFlow Cytometry
FNFunction Assay
GSGel Supershift
IInhibition
IAEnzyme Immunoassay
ICImmunocytochemistry
IDImmunodiffusion
IEImmunoelectrophoresis

IFImmunofluorescence
IGImmunochromatography
IHImmunohistochemistry
IMImmunomicroscopy
IOImmunoassay
IPImmunoprecipitation
ISIntracellular Staining for Flow Cytometry
LALuminex Assay
LFLateral Flow Immunoassay
MMicroarray
MCMass Cytometry/CyTOF
MDMeDIP

MSElectrophoretic Mobility Shift Assay
NNeutralization
PImmunohistologyp-Paraffin Sections
PAPeptide Array
PEPeptide ELISA
PLProximity Ligation Assay
RRadioimmunoassay
SStimulation
SESandwich ELISA
SHIn situ hybridization
TCTissue Culture
WBWestern Blot

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