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Mouse Anti-BAK1 Recombinant Antibody (4C2) (CBMAB-BR052LY)

The product is antibody recognizes BAK1. The antibody 4C2 immunoassay techniques such as: FC, IF, IHC-P, ICC, WB.
Host Species
Mouse
Application
FC: 1-3 μg/1x10 cells, IF: 1:1000 dilution, IHC-P: 0.5-1 μg/ml, ICC: 1:200 dilution, WB: 0.1-0.5 μg/ml
Immunogen
E.coli-derived human BAK/BAK1 recombinant protein (Position: A22-S211)
Antibody Isotype
IgG2b
Specificity
Human, Mouse, Rat
Clone
4C2
Format
Lyophilized
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.
Introduction
The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form oligomers or heterodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein localizes to mitochondria, and functions to induce apoptosis. It interacts with and accelerates the opening of the mitochondrial voltage-dependent anion channel, which leads to a loss in membrane potential and the release of cytochrome c. This protein also interacts with the tumor suppressor P53 after exposure to cell stress. [provided by RefSeq, Jul 2008]
Alternative Name
Bcl-2 homologous antagonist/killer; Apoptosis regulator BAK; Bcl-2-like protein 7; Bcl2-L-7; BAK1; BAK; BCL2L7; CDN1
Entrez Gene ID
Human578
Mouse12018
Rat116502
UniProt ID
HumanQ16611
MouseO08734
RatQ9JK59
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For research use only. Not intended for any clinical use.
Cat CBMAB-BR052LY
Conjugates
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Second antibody and isotype control