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Mouse Anti-BANP Recombinant Antibody (CBYY-1874) (CBMAB-2223-YY)

This product is mouse antibody that recognizes BANP. The antibody CBYY-1874 can be used for immunoassay techniques such as: ELISA, WB, IHC-P
See all BANP antibodies

Summary

Host Animal
Mouse
Specificity
Human, Mouse, Rat
Clone
CBYY-1874
Antibody Isotype
IgG1, κ
Application
WB, IP

Basic Information

Immunogen
Amino acids 30-390 of BANP of human origin.
Specificity
Human, Mouse, Rat
Antibody Isotype
IgG1, κ
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.
ApplicationNote
WB1:100-1:1,000
IP1-2 µg per 100-500 µg of total protein (1 ml of cell lysate)

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, 0.1% gelatin
Preservative
< 0.1% sodium azide
Concentration
0.1 mg/ml
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
BTG3 associated nuclear protein
Introduction
This gene encodes a protein that binds to matrix attachment regions. The protein forMouse a complex with p53 and negatively regulates p53 transcription, and functions as a tumor suppressor and cell cycle regulator. Multiple transcript variants encoding different isoforMouse have been found for this gene. [provided by RefSeq, Mar 2010]
Entrez Gene ID
54971
UniProt ID
Q8N9N5
Alternative Names
BTG3 Associated Nuclear Protein; Scaffold/Matrix-Associated Region-1-Binding Protein; BEN Domain-Containing Protein 1; BEND1; SMAR1; Btg3-Associated Nuclear Protein; BEN Domain Containing 1; Protein BANP; SMARBP1;
Function
Controls V(D)J recombination during T-cell development by repressing T-cell receptor (TCR) beta enhancer function. Binds to scaffold/matrix attachment region beta (S/MARbeta), an ATC-rich DNA sequence located upstream of the TCR beta enhancer. Represses cyclin D1 transcription by recruiting HDAC1 to its promoter, thereby diminishing H3K9ac, H3S10ph and H4K8ac levels. Promotes TP53 activation, which causes cell cycle arrest (By similarity).
Biological Process
Cell cycle Source: UniProtKB-KW
Chromatin organization Source: UniProtKB-KW
Multicellular organism development Source: UniProtKB-KW
Negative regulation of protein catabolic process Source: GO_Central
Positive regulation of transcription, DNA-templated Source: Ensembl
Protein localization to nucleus Source: GO_Central
Regulation of signal transduction by p53 class mediator Source: Reactome
Cellular Location
Nucleus
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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