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BANP

This gene encodes a protein that binds to matrix attachment regions. The protein forms a complex with p53 and negatively regulates p53 transcription, and functions as a tumor suppressor and cell cycle regulator. Multiple transcript variants encoding different isoforms have been found for this gene.

Full Name

BTG3 associated nuclear protein

Function

Controls V(D)J recombination during T-cell development by repressing T-cell receptor (TCR) beta enhancer function. Binds to scaffold/matrix attachment region beta (S/MARbeta), an ATC-rich DNA sequence located upstream of the TCR beta enhancer. Represses cyclin D1 transcription by recruiting HDAC1 to its promoter, thereby diminishing H3K9ac, H3S10ph and H4K8ac levels. Promotes TP53 activation, which causes cell cycle arrest (By similarity).

Biological Process

Cell cycle Source: UniProtKB-KW
Chromatin organization Source: UniProtKB-KW
Multicellular organism development Source: UniProtKB-KW
Negative regulation of protein catabolic process Source: GO_Central
Positive regulation of transcription, DNA-templated Source: Ensembl
Protein localization to nucleus Source: GO_Central
Regulation of signal transduction by p53 class mediator Source: Reactome

Cellular Location

Nucleus

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Anti-BANP antibodies

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Human BANP ELISA Kit (V2LY-0626-LY3477)

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Target: BANP

Sensitivity: 0.024 ng/mL

Detection Range: 0.05-30 ng/mL

Sample Type: Serum, Plasma, cell culture supernates

Specificity: Human

Assay Type: Sandwich

Reactivity: Human

Human BANP ELISA Kit

Mouse Anti-BANP Recombinant Antibody (CBYY-1878) (CBMAB-2227-YY)

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Target: BANP

Host: Mouse

Antibody Isotype: IgG1, κ

Specificity: Human

Clone: CBYY-1878

Application*: P, WB

Mouse Anti-BANP Recombinant Antibody (CBYY-1878)

Mouse Anti-BANP Recombinant Antibody (CBYY-1874) (CBMAB-2223-YY)

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Target: BANP

Host: Mouse

Antibody Isotype: IgG1, κ

Specificity: Human, Mouse, Rat

Clone: CBYY-1874

Application*: WB, IP

Mouse Anti-BANP Recombinant Antibody (CBYY-1874)

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Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized)

Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

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Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized)

Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

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(P): Predicted

* Abbreviations

AActivation
AGAgonist
APApoptosis
BBlocking
BABioassay
BIBioimaging
CImmunohistochemistry-Frozen Sections
CIChromatin Immunoprecipitation
CTCytotoxicity
CSCostimulation
DDepletion
DBDot Blot

EELISA
ECELISA(Cap)
EDELISA(Det)
ESELISpot
EMElectron Microscopy
FFlow Cytometry
FNFunction Assay
GSGel Supershift
IInhibition
IAEnzyme Immunoassay
ICImmunocytochemistry
IDImmunodiffusion
IEImmunoelectrophoresis

IFImmunofluorescence
IGImmunochromatography
IHImmunohistochemistry
IMImmunomicroscopy
IOImmunoassay
IPImmunoprecipitation
ISIntracellular Staining for Flow Cytometry
LALuminex Assay
LFLateral Flow Immunoassay
MMicroarray
MCMass Cytometry/CyTOF
MDMeDIP

MSElectrophoretic Mobility Shift Assay
NNeutralization
PImmunohistologyp-Paraffin Sections
PAPeptide Array
PEPeptide ELISA
PLProximity Ligation Assay
RRadioimmunoassay
SStimulation
SESandwich ELISA
SHIn situ hybridization
TCTissue Culture
WBWestern Blot

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